Bacterial persisters: molecular mechanisms and therapeutic development

H Niu, J Gu, Y Zhang - Signal transduction and targeted therapy, 2024 - nature.com
Persisters refer to genetically drug susceptible quiescent (non-growing or slow growing)
bacteria that survive in stress environments such as antibiotic exposure, acidic and …

Antimicrobial resistance: more than 70 years of war between humans and bacteria

SF Nadeem, UF Gohar, SF Tahir… - Critical Reviews in …, 2020 - Taylor & Francis
Abstract Development of antibiotic resistance in bacteria is one of the major issues in the
present world and one of the greatest threats faced by mankind. Resistance is spread …

[HTML][HTML] Antimicrobial peptides: Opportunities and challenges in overcoming resistance

C Bucataru, C Ciobanasu - Microbiological Research, 2024 - Elsevier
Antibiotic resistance represents a global health threat, challenging the efficacy of traditional
antimicrobial agents and necessitating innovative approaches to combat infectious …

Bacterial biofilm infections, their resistance to antibiotics therapy and current treatment strategies

A Singh, A Amod, P Pandey, P Bose… - Biomedical …, 2022 - iopscience.iop.org
Nearly 80% of human chronic infections are caused due to bacterial biofilm formation. This
is the most leading cause for failure of medical implants resulting in high morbidity and …

Inhibiting bacterial drug efflux pumps via phyto-therapeutics to combat threatening antimicrobial resistance

V Shriram, T Khare, R Bhagwat, R Shukla… - Frontiers in …, 2018 - frontiersin.org
Antibiotics, once considered the lifeline for treating bacterial infections, are under threat due
to the emergence of threatening antimicrobial resistance (AMR). These drug-resistant …

The mechanism of bacterial resistance and potential bacteriostatic strategies

F Zhang, W Cheng - Antibiotics, 2022 - mdpi.com
Bacterial drug resistance is rapidly developing as one of the greatest threats to human
health. Bacteria will adopt corresponding strategies to crack the inhibitory effect of antibiotics …

Comparison of antibiotic resistance mechanisms in antibiotic-producing and pathogenic bacteria

H Ogawara - Molecules, 2019 - mdpi.com
Antibiotic resistance poses a tremendous threat to human health. To overcome this problem,
it is essential to know the mechanism of antibiotic resistance in antibiotic-producing and …

Flavonoids as inhibitors of bacterial efflux pumps

M Waditzer, F Bucar - Molecules, 2021 - mdpi.com
Flavonoids are widely occurring secondary plant constituents, and are abundant in
vegetable and fruit diets as well as herbal medicines. Therapeutic treatment options for …

Recent advances in the treatment of pathogenic infections using antibiotics and nano-drug delivery vehicles

V Van Giau, SSA An, J Hulme - Drug design, development and …, 2019 - Taylor & Francis
The worldwide misuse of antibiotics and the subsequent rise of multidrug-resistant
pathogenic bacteria have prompted a paradigm shift in the established view of antibiotic and …

Nanosilver: An old antibacterial agent with great promise in the fight against antibiotic resistance

KG Kaiser, V Delattre, VJ Frost, GW Buck, JV Phu… - Antibiotics, 2023 - mdpi.com
Antibiotic resistance in bacteria is a major problem worldwide that costs 55 billion USD
annually for extended hospitalization, resource utilization, and additional treatment …