Transforming growth factor-βs (TGF-βs) and bone morphometric proteins (BMPs) belong to
the TGF-β superfamily and perform essential functions during osteoblast and chondrocyte …

Mesenchymal stem cells (MSCs) can differentiate into several lineages during development
and also contribute to tissue homeostasis and regeneration, although the requirements for …

Progress toward finding a cure for muscle diseases has been slow because of the absence
of relevant cellular models and the lack of a reliable source of muscle progenitors for …

Skeletal stem cells (SSCs) reside in the postnatal bone marrow and give rise to cartilage,
bone, hematopoiesis-supportive stroma and marrow adipocytes in defined in vivo assays …

The establishment of human induced pluripotent stem cells (hiPSCs) has enabled the
production of in vitro, patient-specific cell models of human disease. In vitro recreation of …

The translational potential of mesenchymal stem/stromal cells (MSCs) is limited by their
rarity in somatic organs, heterogeneity, and need for harvest by invasive procedures …

Mesenchymal stem cells (MSCs) are being tested in a wide range of human diseases;
however, loss of potency and inconsistent quality severely limit their use. To overcome these …

The use of mesenchymal stem cells (MSCs) for clinical purposes has skyrocketed in the past
decade. Their multilineage differentiation potentials and immunomodulatory properties have …

Background Current studies have enlightened the rosy prospects of human pluripotent stem
cell (hPSC)-derived mesenchymal stem/stromal cells (MSCs) in regenerative medicine …

Avascular, aneural articular cartilage has a low capacity for self‐repair and as a
consequence is highly susceptible to degradative diseases such as osteoarthritis. Thus the …