Periodontitis and cardiovascular diseases: Consensus report

M Sanz, A Marco del Castillo, S Jepsen… - Journal of clinical …, 2020 - Wiley Online Library
Abstract Background In Europe cardiovascular disease (CVD) is responsible for 3.9 million
deaths (45% of deaths), being ischaemic heart disease, stroke, hypertension (leading to …

Chitosan-based scaffolds as drug delivery systems in bone tissue engineering

R Bharathi, SS Ganesh, G Harini, K Vatsala… - International Journal of …, 2022 - Elsevier
The bone tissue engineering approach for treating large bone defects becomes necessary
when the tissue damage surpasses the threshold of the inherent regenerative ability of the …

Osteoblast-derived VEGF regulates osteoblast differentiation and bone formation during bone repair

K Hu, BR Olsen - The Journal of clinical investigation, 2016 - Am Soc Clin Investig
Osteoblast-derived VEGF is important for bone development and postnatal bone
homeostasis. Previous studies have demonstrated that VEGF affects bone repair and …

Oxidized phospholipids, lipoprotein (a), and progression of calcific aortic valve stenosis

R Capoulade, KL Chan, C Yeang, P Mathieu… - Journal of the American …, 2015 - jacc.org
Abstract Background: Elevated lipoprotein (a)(Lp [a]) is associated with aortic stenosis (AS).
Oxidized phospholipids (OxPL) are key mediators of calcification in valvular cells and are …

[HTML][HTML] Suppl 1: A brief historical perspective on dental implants, their surface coatings and treatments

CM Abraham - The open dentistry journal, 2014 - ncbi.nlm.nih.gov
This review highlights a brief, chronological sequence of the history of dental implants. This
historical perspective begins with ancient civilizations and spotlights predominant dentists …

[HTML][HTML] Potential bioactive coating system for high-performance absorbable magnesium bone implants

MN Sarian, N Iqbal, P Sotoudehbagha, M Razavi… - Bioactive Materials, 2022 - Elsevier
Magnesium alloys are considered the most suitable absorbable metals for bone fracture
fixation implants. The main challenge in absorbable magnesium alloys is their high …

Structural mechanism for statin inhibition of HMG-CoA reductase

ES Istvan, J Deisenhofer - Science, 2001 - science.org
HMG-CoA (3-hydroxy-3-methylglutaryl–coenzyme A) reductase (HMGR) catalyzes the
committed step in cholesterol biosynthesis. Statins are HMGR inhibitors with inhibition …

Environment-mediated drug resistance: a major contributor to minimal residual disease

MB Meads, RA Gatenby, WS Dalton - Nature reviews cancer, 2009 - nature.com
Environment-mediated drug resistance is a form of de novo drug resistance that protects
tumour cells from the initial effects of diverse therapies. Surviving foci of residual disease …

[HTML][HTML] Implant surface characteristics and their effect on osseointegration

A Barfeie, J Wilson, J Rees - British dental journal, 2015 - nature.com
Aim The aim of this literature review is to find current knowledge of dental implants focusing
on materials, designs and surface modifications and to understand which implant surfaces …

Pleiotropic effects of statins

JK Liao, U Laufs - Annu. Rev. Pharmacol. Toxicol., 2005 - annualreviews.org
▪ Abstract Statins are potent inhibitors of cholesterol biosynthesis. In clinical trials, statins are
beneficial in the primary and secondary prevention of coronary heart disease. However, the …