Elucidating the reinforcing effects of nicotine: a tribute to Nadia Chaudhri

AF Sved, AR Caggiula, EC Donny - Psychopharmacology, 2023 - Springer
Nadia Chaudhri worked with us as a graduate student in the Center for Neuroscience at the
University of Pittsburgh from 1999 until she earned her PhD in 2005, a time that coincided …

Individual variations in motives for nicotine self-administration in male rats: evidence in support for a precision psychopharmacology

V Garcia-Rivas, JF Fiancette, J Tostain… - Translational …, 2024 - nature.com
The significant heterogeneity in smoking behavior among smokers, coupled with the
inconsistent efficacy of approved smoking cessation therapies, supports the presence of …

Nicotine but not saline self-administering or yoked control conditions produces sustained neuroadaptations in the accumbens shell

A Domi, E Lucente, D Cadeddu… - Frontiers in molecular …, 2023 - frontiersin.org
Introduction Using yoked animals as the control when monitoring operant drug-self-
administration is considered the golden standard. However, instrumental learning per se …

Significant association of nicotine reinforcement and cue reactivity: a translational study in humans and rats

K Butler, B Forget, SJ Heishman… - Behavioural …, 2021 - journals.lww.com
Relapse is common amongst smokers attempting to quit and tobacco cue-induced craving is
an important relapse mechanism. Preclinical studies commonly use cue-induced …

Varenicline but not cotinine increased the value of a visual stimulus reinforcer in rats: No evidence for synergy of the two compounds

SD Houser, KR McNealy, ST Barrett… - … Biochemistry and Behavior, 2024 - Elsevier
Smoking is the leading cause of preventable death worldwide, with< 7% of smoking
cessation attempts being met with success. Nicotine, the main addictive agent in cigarettes …

Assessment of individual differences in response to acute bupropion or varenicline treatment using a long-access nicotine self-administration model and behavioral …

T Kazan, CL Robison, N Cova, VM Madore… - Behavioural brain …, 2020 - Elsevier
Bupropion and varenicline are widely prescribed pharmacological treatments for smoking
cessation. These treatments are only marginally effective in clinical populations but most …

Individual variations in motives for nicotine self-administration in rats: evidence in support for a precision psychopharmacology

V Deroche-Gamonet, V Garcia-Rivas, JF Fiancette… - 2023 - researchsquare.com
The significant heterogeneity in smoking behavior among smokers, coupled with the
inconsistent efficacy of approved smoking cessation therapies, supports the presence of …

Preclinical Models of Relapse to Psychostimulants Induced by Environmental Stimuli

AM Borruto, A Domi, L Soverchia, E Domi, H Li… - Methods for Preclinical …, 2022 - Springer
A major aim of addiction research is the understanding of the pathophysiological profile of
relapse risk and the development of treatments for relapse prevention. Exposure to drug …

Evidence of individual differences in motives for nicotine seeking in classical nicotine self-administration and associated outcomes of varenicline administration

V Garcia-Rivas, JF Fiancette, J Tostain, G de Maio… - bioRxiv, 2021 - biorxiv.org
Background Smokers vary in their motives for tobacco seeking, suggesting that they could
benefit from personalized treatments. However, these variations have received little attention …