Ferrocene-appended pharmacophores: An exciting approach for modulating the biological potential of organic scaffolds
Two exemplary contributions of organometallics in medicinal chemistry, ferroquine and
ferrocifen, which exhibit excellent anti-plasmodial and anti-cancer activities, respectively …
ferrocifen, which exhibit excellent anti-plasmodial and anti-cancer activities, respectively …
Enhancing the activity of drugs by conjugation to organometallic fragments
P Chellan, PJ Sadler - Chemistry–A European Journal, 2020 - Wiley Online Library
Resistance to chemotherapy is a current clinical problem, especially in the treatment of
microbial infections and cancer. One strategy to overcome this is to make new derivatives of …
microbial infections and cancer. One strategy to overcome this is to make new derivatives of …
Emerging impact of triazoles as anti-tubercular agent
A Sharma, AK Agrahari, S Rajkhowa… - European Journal of …, 2022 - Elsevier
Tuberculosis, a disease of poverty is a communicable infection with a reasonably high
mortality rate worldwide. 10 Million new cases of TB were reported with approx 1.4 million …
mortality rate worldwide. 10 Million new cases of TB were reported with approx 1.4 million …
Ferrocene derivatives as anti-infective agents
BS Ludwig, JDG Correia, FE Kühn - Coordination Chemistry Reviews, 2019 - Elsevier
Infectious diseases like malaria, tuberculosis or HIV are among the leading causes of death
worldwide according to WHO estimations. Nevertheless, the fight against infectious diseases …
worldwide according to WHO estimations. Nevertheless, the fight against infectious diseases …
[HTML][HTML] Recent advances in chalcone-triazole hybrids as potential pharmacological agents
Molecular hybridization is one of the recent strategies to synthesize a novel hybrid
compound by combining two or more pharmacophoric units. Being a linkage process, it …
compound by combining two or more pharmacophoric units. Being a linkage process, it …
Therapeutic potential of uracil and its derivatives in countering pathogenic and physiological disorders
Uracil is one of the most notable pharmacophores in medicinal chemistry as the pyrimidine
nucleobase forms an integral part of many commercial drugs. Though the name uracil is …
nucleobase forms an integral part of many commercial drugs. Though the name uracil is …
An updated review on the synthesis and antibacterial activity of molecular hybrids and conjugates bearing imidazole moiety
R Rossi, M Ciofalo - Molecules, 2020 - mdpi.com
The rapid growth of serious infections caused by antibiotic resistant bacteria, especially the
nosocomial ESKAPE pathogens, has been acknowledged by Governments and scientists …
nosocomial ESKAPE pathogens, has been acknowledged by Governments and scientists …
Ultrasound promoted stereoselective synthesis of 2, 3-dihydrobenzofuran appended chalcones at ambient temperature
VA Adole, BS Jagdale, TB Pawar, AA Sagane - South african journal of …, 2020 - ajol.info
In the present investigation, an ultrasound promoted the synthesis of a series of (E)-3-(2, 3-
dihydrobenzofuran 5-yl)-1-(aryl) prop-2-en-1-one derivatives from 2, 3-dihydrobenzofuran-5 …
dihydrobenzofuran 5-yl)-1-(aryl) prop-2-en-1-one derivatives from 2, 3-dihydrobenzofuran-5 …
A strategic approach to the synthesis of ferrocene appended chalcone linked triazole allied organosilatranes: Antibacterial, antifungal, antiparasitic and antioxidant …
G Singh, A Arora, P Kalra, IK Maurya, CE Ruizc… - Bioorganic & Medicinal …, 2019 - Elsevier
A series of ferrocene appended chalcone allied triazole coupled organosilatranes (FCTSa 7–
FCTSa 12) were synthesised with the aim of amalgamating the pharmacological action of …
FCTSa 12) were synthesised with the aim of amalgamating the pharmacological action of …
Ferrocene-triazole conjugates: do we know why they are biologically active?
M Koszytkowska-Stawińska, W Buchowicz - Dalton Transactions, 2023 - pubs.rsc.org
The bioorganometallic chemistry of ferrocene has been gaining significance in recent years.
This review presents ferrocene-triazole conjugates displaying significant biological …
This review presents ferrocene-triazole conjugates displaying significant biological …