Ferrocene-appended pharmacophores: An exciting approach for modulating the biological potential of organic scaffolds

A Singh, I Lumb, V Mehra, V Kumar - Dalton transactions, 2019 - pubs.rsc.org
Two exemplary contributions of organometallics in medicinal chemistry, ferroquine and
ferrocifen, which exhibit excellent anti-plasmodial and anti-cancer activities, respectively …

Enhancing the activity of drugs by conjugation to organometallic fragments

P Chellan, PJ Sadler - Chemistry–A European Journal, 2020 - Wiley Online Library
Resistance to chemotherapy is a current clinical problem, especially in the treatment of
microbial infections and cancer. One strategy to overcome this is to make new derivatives of …

Emerging impact of triazoles as anti-tubercular agent

A Sharma, AK Agrahari, S Rajkhowa… - European Journal of …, 2022 - Elsevier
Tuberculosis, a disease of poverty is a communicable infection with a reasonably high
mortality rate worldwide. 10 Million new cases of TB were reported with approx 1.4 million …

Ferrocene derivatives as anti-infective agents

BS Ludwig, JDG Correia, FE Kühn - Coordination Chemistry Reviews, 2019 - Elsevier
Infectious diseases like malaria, tuberculosis or HIV are among the leading causes of death
worldwide according to WHO estimations. Nevertheless, the fight against infectious diseases …

[HTML][HTML] Recent advances in chalcone-triazole hybrids as potential pharmacological agents

A Bhukal, V Kumar, L Kumar, K Lal - Results in Chemistry, 2023 - Elsevier
Molecular hybridization is one of the recent strategies to synthesize a novel hybrid
compound by combining two or more pharmacophoric units. Being a linkage process, it …

Therapeutic potential of uracil and its derivatives in countering pathogenic and physiological disorders

D Ramesh, BG Vijayakumar, T Kannan - European journal of medicinal …, 2020 - Elsevier
Uracil is one of the most notable pharmacophores in medicinal chemistry as the pyrimidine
nucleobase forms an integral part of many commercial drugs. Though the name uracil is …

An updated review on the synthesis and antibacterial activity of molecular hybrids and conjugates bearing imidazole moiety

R Rossi, M Ciofalo - Molecules, 2020 - mdpi.com
The rapid growth of serious infections caused by antibiotic resistant bacteria, especially the
nosocomial ESKAPE pathogens, has been acknowledged by Governments and scientists …

Ultrasound promoted stereoselective synthesis of 2, 3-dihydrobenzofuran appended chalcones at ambient temperature

VA Adole, BS Jagdale, TB Pawar, AA Sagane - South african journal of …, 2020 - ajol.info
In the present investigation, an ultrasound promoted the synthesis of a series of (E)-3-(2, 3-
dihydrobenzofuran 5-yl)-1-(aryl) prop-2-en-1-one derivatives from 2, 3-dihydrobenzofuran-5 …

A strategic approach to the synthesis of ferrocene appended chalcone linked triazole allied organosilatranes: Antibacterial, antifungal, antiparasitic and antioxidant …

G Singh, A Arora, P Kalra, IK Maurya, CE Ruizc… - Bioorganic & Medicinal …, 2019 - Elsevier
A series of ferrocene appended chalcone allied triazole coupled organosilatranes (FCTSa 7–
FCTSa 12) were synthesised with the aim of amalgamating the pharmacological action of …

Ferrocene-triazole conjugates: do we know why they are biologically active?

M Koszytkowska-Stawińska, W Buchowicz - Dalton Transactions, 2023 - pubs.rsc.org
The bioorganometallic chemistry of ferrocene has been gaining significance in recent years.
This review presents ferrocene-triazole conjugates displaying significant biological …