Pyoderma gangrenosum: an updated literature review on established and emerging pharmacological treatments

CA Maronese, MA Pimentel, MM Li… - American Journal of …, 2022 - Springer
Pyoderma gangrenosum is a rare inflammatory skin disease classified within the group of
neutrophilic dermatoses and clinically characterized by painful, rapidly evolving cutaneous …

Pyoderma gangrenosum

E Maverakis, AV Marzano, ST Le, JP Callen… - Nature Reviews …, 2020 - nature.com
Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis that presents with rapidly
developing, painful skin ulcers hallmarked by undermined borders and peripheral erythema …

Atypical wounds. Best clinical practice and challenges

K Isoherranen, JJ O'Brien, J Barker… - Journal of wound …, 2019 - magonlinelibrary.com
Atypical wounds comprise approximately 20% of all chronic wounds. 3–5 With an aging
population and increase in comorbidities these numbers are expected to rise. Atypical …

[HTML][HTML] Proprotein convertase subtilisin/kexin type 9 is a psoriasis-susceptibility locus that is negatively related to IL36G

A Merleev, A Ji-Xu, A Toussi, LC Tsoi, ST Le… - JCI insight, 2022 - ncbi.nlm.nih.gov
Proprotein convertase subtilisin/kexin type-9 (PCSK9) is a posttranslational regulator of the
LDL receptor (LDLR). Recent studies have proposed a role for PCSK9 in regulating immune …

[HTML][HTML] Recent advances in managing and understanding pyoderma gangrenosum

J Fletcher, R Alhusayen, A Alavi - F1000Research, 2019 - ncbi.nlm.nih.gov
Pyoderma Gangrenosum (PG) is a rare neutrophilic dermatosis with multiple different
clinical presentations and associated comorbidities. PG has historically been a challenging …

Pyoderma gangrenosum: A systematic review of the molecular characteristics of disease

A Flora, E Kozera, JW Frew - Experimental Dermatology, 2022 - Wiley Online Library
Pyoderma gangrenosum is a painful recurrent ulcerative neutrophilic dermatosis in which
the pathogenesis is incompletely defined. Current evidence suggests that PG is associated …

[PDF][PDF] Molecular and cellular characterization of pyoderma gangrenosum: implications for the use of gene expression

AG Ortega-Loayza, MA Friedman, AM Reese… - Journal of Investigative …, 2021 - air.unimi.it
CAPNS2, ADAMTS14, FN1, BGN, MMP10, MMP12, MMP11, MMP13, PXDN, MMP19, SPP1,
COL22A1, C OL3A1, COL17A1, ITGAM, ITGB3, ITGB2, ITGAL, I TGAX, ITGA4, ITGA1 …

Pyoderma gangrenosum: a review of updates in diagnosis, pathophysiology and management

M Skopis, A Bag-Ozbek - J, 2021 - mdpi.com
Pyoderma gangrenosum (PG) is a rare entity that is characterized by infiltration of
neutrophils into the dermis, causing the formation of rapidly enlarging, painful and necrotic …

Cutaneous manifestations of inflammatory bowel disease: basic characteristics, therapy, and potential pathophysiological associations

R He, S Zhao, M Cui, Y Chen, J Ma, J Li… - Frontiers in …, 2023 - frontiersin.org
Inflammatory bowel disease (IBD) is a chronic inflammatory disease typically involving the
gastrointestinal tract but not limited to it. IBD can be subdivided into Crohn's disease (CD) …

Pyoderma gangrenosum in hematologic malignancies: a systematic review

CM Montagnon, EA Fracica, AA Patel… - Journal of the American …, 2020 - Elsevier
Background Pyoderma gangrenosum (PG) is a devastating neutrophilic dermatosis that may
be associated with trauma or systemic diseases. The associations, characteristics, and …