Most efforts aimed at understanding the notable heterogeneity of outcomes in multiple
sclerosis (MS) have focused on disease-specific factors, such as symptoms at initial …

Despite that it is commonly accepted that migraine is a disorder of the nervous system with a
prominent genetic basis, it is comorbid with a plethora of medical conditions. Several studies …

Pharmacological treatment of pain in multiple sclerosis (MS) is challenging due to the many
underlying pathophysiological mechanisms. Few controlled trials show adequate pain …

Migraine headaches are highly prevalent, affecting 15% of the population. However, despite
many studies to determine this disease's mechanism and efficient management, its …

Several lines of evidence support a role of the immune system in headache pathogenesis,
with particular regard to migraine. Firstly, alterations in cytokine profile and in lymphocyte …

Objective: To determine the prevalence of comorbidity in the multiple sclerosis (MS)
population at the time of MS diagnosis. We also compared the prevalence of comorbidity in …

Abstract Purpose of Review Comorbid conditions, secondary conditions, and health
behaviors are increasingly recognized to be important factors influencing a range of …

Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the
central nervous system (CNS) affecting more than two million people worldwide. In MS …

Multiple sclerosis (MS) is a multifaceted, complex and chronic neurological disease that
leads to motor, sensory and cognitive deficits. MS symptoms are unpredictable and …

Objectives We designed this systematic review to estimate pooled prevalence of migraine in
patients with multiple sclerosis (MS). Methods We searched PubMed, Scopus, EMBASE …