Peroxisomes are subcellular organelles that play a central role in human physiology by
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …

Peroxisomes are dynamic organelles that play an essential role in a variety of cellular
catabolic and anabolic metabolic pathways, including fatty acid alpha-and beta-oxidation …

Peroxisomes are unique subcellular organelles which play an indispensable role in several
key metabolic pathways which include:(1.) etherphospholipid biosynthesis;(2.) fatty acid …

▪ Abstract The synthesis and excretion of bile acids comprise the major pathway of
cholesterol catabolism in mammals. Synthesis provides a direct means of converting …

In this review, we describe the current state of knowledge about the biochemistry of
mammalian peroxisomes, especially human peroxisomes. The identification and …

Abstract α-Methylacyl-CoA racemase (AMACR) is a mitochondrial and peroxisomal enzyme
involved in the metabolism of branched-chain fatty acid and bile acid intermediates …

Peroxisomes are subcellular organelles with an indispensable role in cellular metabolism.
The importance of peroxisomes for humans is stressed by the existence of a group of …

▪ Abstract Fifteen years ago, we had a model of peroxisome biogenesis that involved growth
and division of preexisting peroxisomes. Today, thanks to genetically tractable model …

An increasing body of evidence suggests that mitochondrial dysfunction plays an important
role in the pathogenesis of familial amyotrophic lateral sclerosis associated with “gain of …

α-methylacyl CoA racemase (AMACR), also known as P504S, plays an important role in
peroxisomal beta-oxidation of branched-chain fatty acids. It has recently been shown that …