The spectrin-based membrane skeleton of the humble mammalian erythrocyte has provided
biologists with a set of interacting proteins with diverse roles in organization and survival of …

Plasma membranes of metazoan cells are the site of convergence of disparate sets of
molecules located in intercellular, transmembrane, and cytoplasmic compartments …

The complete sequence of the human Duchenne muscular dystrophy (DMD) cDNA has
been determined. The 3685 encoded amino acids of the protein product, dystrophin, can be …

A novel Mr 28,000 integral membrane protein (" 28kDa") was identified in human
erythrocytes and found entirely associated with the Triton X-100 insoluble membrane …

The stability and shape of the erythrocyte membrane is provided by the ankyrin-1 complex,
but how it tethers the spectrin–actin cytoskeleton to the lipid bilayer and the nature of its …

Abstract Analysis of complementary DNA for human erythroid ankyrin indicates that the
mature protein contains 1,880 amino acids comprising an N-terminal domain binding …

Human T-cell leukemia virus type III (HTLV-III) was recently identified as the probable
etiologic agent of the acquired immune deficiency syndrome (AIDS). Here it is shown that, in …

Skeletal proteins play an important role in determining erythrocyte membrane biophysical
properties. To study whether membrane deformability and stability are regulated by the …

Previous studies point to the acidic amino-terminal segment of band 3, the anion transport
protein of the red cell, as the common binding site for hemoglobin and several of the …

Spectrin is an αβ heterodimeric protein (molecular weight (M r)= 460,000) which is a major
component of the erythrocyte membrane skeleton1–8. The membrane skeleton also …