Rational design of cancer nanomedicine: nanoproperty integration and synchronization
Current cancer nanomedicines can only mitigate adverse effects but fail to enhance
therapeutic efficacies of anticancer drugs. Rational design of next‐generation cancer …
therapeutic efficacies of anticancer drugs. Rational design of next‐generation cancer …
Recent progress in polymer-based platinum drug delivery systems
Platinum drugs comprise of almost 50% of all currently used anticancer drugs. They are now
widely used in the clinical therapy of various solid tumors, including ovarian, head and neck …
widely used in the clinical therapy of various solid tumors, including ovarian, head and neck …
Multifaceted roles of copper ions in anticancer nanomedicine
S Yang, Y Song, Y Hu, HJ Chen… - Advanced Healthcare …, 2023 - Wiley Online Library
The significantly increased copper level in tumor tissues and serum indicates the close
association of copper ions with tumor development, making copper ions attractive targets in …
association of copper ions with tumor development, making copper ions attractive targets in …
Recent advances in pH/enzyme-responsive polysaccharide-small-molecule drug conjugates as nanotherapeutics
Now-a-days, the polysaccharides are extensively employed for the delivery of small-
molecule drugs ascribed to their excellent biocompatibility, biodegradability and …
molecule drugs ascribed to their excellent biocompatibility, biodegradability and …
Polymeric and small molecule-conjugates of temozolomide as improved therapeutic agents for glioblastoma multiforme
Abstract Temozolomide (TMZ), an imidazotetrazine, is a second-generation DNA alkylating
agent used as a first-line treatment of glioblastoma multiforme (GBM). It was approved by …
agent used as a first-line treatment of glioblastoma multiforme (GBM). It was approved by …
Phytochemical based nanomedicines against cancer: current status and future prospects
Cancer continues to be one in all the leading reasons for death worldwide. The mean
cancer survival through standard therapeutic strategies has not been significantly improved …
cancer survival through standard therapeutic strategies has not been significantly improved …
Bioengineered carboxymethylcellulose–peptide hybrid nanozyme cascade for targeted intracellular biocatalytic–magnetothermal therapy of brain cancer cells
AAP Mansur, SM Carvalho, LCA Oliveira… - Pharmaceutics, 2022 - mdpi.com
Glioblastoma remains the most lethal form of brain cancer, where hybrid nanomaterials
biofunctionalized with polysaccharide peptides offer disruptive strategies relying on …
biofunctionalized with polysaccharide peptides offer disruptive strategies relying on …
α-Amylase-and redox-responsive nanoparticles for tumor-targeted drug delivery
Y Li, H Hu, Q Zhou, Y Ao, C Xiao, J Wan… - … applied materials & …, 2017 - ACS Publications
Paclitaxel (PTX) is an effective antineoplastic agent and shows potent antitumor activity
against a wide spectrum of cancers. Yet, the wide clinical use of PTX is limited by its poor …
against a wide spectrum of cancers. Yet, the wide clinical use of PTX is limited by its poor …
Design and development of polysaccharide-doxorubicin-peptide bioconjugates for dual synergistic effects of integrin-targeted and cell-penetrating peptides for cancer …
AAP Mansur, SM Carvalho, ZIP Lobato… - Bioconjugate …, 2018 - ACS Publications
Polymer-drug conjugation is an attractive approach for target delivering insoluble and highly
toxic drugs to tumor sites to overcome the side-effects caused by cancer chemotherapy. In …
toxic drugs to tumor sites to overcome the side-effects caused by cancer chemotherapy. In …
Rethinking nanoparticulate polymer–drug conjugates for cancer theranostics
Polymer–drug conjugates (PDCs) fabricated as nanoparticles have hogged the limelight in
cancer theranostics in the past decade. Many researchers have devoted to developing novel …
cancer theranostics in the past decade. Many researchers have devoted to developing novel …