Cardiovascular immunotoxicities associated with immune checkpoint inhibitors: a safety meta-analysis

C Dolladille, J Akroun, PM Morice… - European Heart …, 2021 - academic.oup.com
Aims The risk and incidence of cardiovascular (CV) immune-related adverse events (irAEs)
associated with immune checkpoint inhibitors (ICIs) in cancer patients remain unknown …

Cardiac toxicity associated with immune checkpoint inhibitors: a systematic review

W Shalata, A Abu-Salman, R Steckbeck… - Cancers, 2021 - mdpi.com
Simple Summary This review article addresses the toxic effects on the heart associated with
the use of certain cancer-treating drugs known as immune checkpoint inhibitors. These …

2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic …

AR Lyon, T Lopez-Fernandez, LS Couch… - European Heart …, 2022 - academic.oup.com
ESC Guidelines e341 (1) the specific situation of the patient. In this respect, it is specified
that, unless otherwise provided for by national regulations, offlabel use of medication should …

Cardiovascular complications of immune checkpoint inhibitors for cancer

F Thuny, J Naidoo, TG Neilan - European heart journal, 2022 - academic.oup.com
Over the last decade or so, there has been a paradigm shift in the oncologic care of patients
with a range of solid tumour and haematologic malignancies, away from traditional cytotoxic …

Immunomodulatory potential of natural products from herbal medicines as immune checkpoints inhibitors: Helping to fight against cancer via multiple targets

Z Zhong, CT Vong, F Chen, H Tan… - Medicinal Research …, 2022 - Wiley Online Library
Immunotherapy sheds new light to cancer treatment and is satisfied by cancer patients.
However, immunotoxicity, single‐source antibodies, and single‐targeting stratege are …

Atherosclerosis With Immune Checkpoint Inhibitor Therapy: Evidence, Diagnosis, and Management: JACC: CardioOncology State-of-the-Art Review

GA Suero-Abreu, MV Zanni, TG Neilan - Cardio Oncology, 2022 - jacc.org
As the clinical applications of immune checkpoint inhibitors (ICIs) expand, our knowledge of
the potential adverse effects of these drugs continues to broaden. Emerging evidence …

[HTML][HTML] Согласованное мнение российских экспертов по профилактике, диагностике и лечению сердечно-сосудистой токсичности противоопухолевой …

ЮА Васюк, ГЕ Гендлин, ЕИ Емелина… - Российский …, 2021 - cyberleninka.ru
АВ—атриовентрикулярный (ая) АГ—артериальная гипертензия АД—артериальное
давление АТ—артериальный тромбоз АТО—атеротромботические осложнения АТФ …

Incidence of cardiovascular events in patients treated with immune checkpoint inhibitors

D Laenens, Y Yu, B Santens, J Jacobs… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE In rare cases, immune checkpoint inhibitors (ICIs) cause immune-mediated
myocarditis. However, true incidence of other major adverse cardiovascular events (MACEs) …

Characterization of immune checkpoint inhibitor‐induced cardiotoxicity reveals interleukin‐17A as a driver of cardiac dysfunction after anti‐PD‐1 treatment

TG Gergely, D Kucsera, VE Tóth… - British Journal of …, 2023 - Wiley Online Library
Background and Purpose Immune checkpoint inhibitors (ICI), such as anti‐PD‐1
monoclonal antibodies, have revolutionized cancer therapy by enhancing the cytotoxic …

Cardiotoxicities of novel cancer immunotherapies

AF Stein-Merlob, MV Rothberg, A Ribas, EH Yang - Heart, 2021 - heart.bmj.com
Immunotherapy revolutionised oncology by harnessing the native immune system to
effectively treat a wide variety of malignancies even at advanced stages. Off-target immune …