Simple Summary Interferons are cytokines that play key roles in the activation of cellular
components of the immune response, such as dendritic cells, macrophages and T cells …

The innate immune pathway is receiving increasing attention in cancer therapy. This
pathway is ubiquitous across various cell types, not only in innate immune cells but also in …

Objectives To better understand how immune responses may be harnessed against breast
cancer, we investigated which immune cell types and signalling pathways are required for …

Cancers evade the immune system through the process of cancer immunoediting. While
immune checkpoint inhibitors are effective for reactivating tumour immunity in some cancer …

Immune checkpoint inhibitors (ICIs) induce a durable response in a wide range of tumor
types, but only a minority of patients outside these 'responsive'tumor types respond, with …

The breast cancer tumor microenvironment (TME) is dynamic, with various immune and non-
immune cells interacting to regulate tumor progression and anti-tumor immunity. It is now …

Intercellular communication plays an essential role in lung cancer (LC). One of the major
players in cell‐cell‐communication is small extracellular vesicles (sEV). SEV trigger various …

Simple Summary Triple-negative breast cancer (TNBC) is the most aggressive subtype of
breast cancer and has a poor prognosis and higher recurrence rate due to ineffective …

Introduction To overcome mechanisms of primary and secondary resistance to the anti-
tumor immune response, novel targets such as ICOS, LAG3, and TIM3 are currently being …

The breast cancer tumour microenvironment (BC-TME) is characterized by significant
cellular and spatial heterogeneity that has important clinical implications and can affect …