[HTML][HTML] Targeting the nucleolus for cancer intervention
The contribution of the nucleolus to cancer is well established with respect to its traditional
role in facilitating ribosome biogenesis and proliferative capacity. More contemporary …
role in facilitating ribosome biogenesis and proliferative capacity. More contemporary …
[HTML][HTML] A charge-dependent mechanism is responsible for the dynamic accumulation of proteins inside nucleoli
YR Musinova, EY Kananykhina… - … et Biophysica Acta (BBA …, 2015 - Elsevier
The majority of known nucleolar proteins are freely exchanged between the nucleolus and
the surrounding nucleoplasm. One way proteins are retained in the nucleoli is by the …
the surrounding nucleoplasm. One way proteins are retained in the nucleoli is by the …
A novel signature constructed by RNA-binding protein coding genes to improve overall survival prediction of glioma patients
Z Tu, L Shu, J Li, L Wu, C Tao, M Ye, X Zhu… - Frontiers in Cell and …, 2021 - frontiersin.org
RNA binding proteins (RBPs) have been reported to be involved in cancer malignancy but
related functions in glioma have been less studied. Herein, we screened 14 prognostic RBP …
related functions in glioma have been less studied. Herein, we screened 14 prognostic RBP …
Interplay between human nucleolar GNL1 and RPS20 is critical to modulate cell proliferation
R Krishnan, N Boddapati, S Mahalingam - Scientific Reports, 2018 - nature.com
Human Guanine nucleotide binding protein like 1 (GNL1) belongs to HSR1_MMR1
subfamily of nucleolar GTPases. Here, we report for the first time that GNL1 promotes cell …
subfamily of nucleolar GTPases. Here, we report for the first time that GNL1 promotes cell …
Mycoplasma gallisepticum MGA_0676 is a membrane-associated cytotoxic nuclease with a staphylococcal nuclease region essential for nuclear translocation and …
Mycoplasma gallisepticum can infect a wide variety of birds including the commercial
poultry. M. gallisepticum MGA_0676 is a putative lipoprotein, which is similar to bacterial …
poultry. M. gallisepticum MGA_0676 is a putative lipoprotein, which is similar to bacterial …
Guanine Nucleotide-Binding Protein-Like 1 (GNL1) binds RNA G-quadruplex structures in genes associated with Parkinson's disease
MA Turcotte, JM Garant, H Cossette-Roberge… - RNA biology, 2021 - Taylor & Francis
RNAs are highly regulated at the post-transcriptional level in neurodegenerative diseases
and just a few mutations can significantly affect the fate of neuronal cells. To date, the impact …
and just a few mutations can significantly affect the fate of neuronal cells. To date, the impact …
Guanine nucleotide binding protein like-1 (GNL1) promotes cancer cell proliferation and survival through AKT/p21 CIP1 signaling cascade
R Krishnan, M Murugiah, NP Lakshmi… - Molecular biology of …, 2020 - Am Soc Cell Biol
Human guanine nucleotide binding protein like 1 (GNL1) is an evolutionary conserved
putative nucleolar GTPase belonging to the HSR1_MMR1 subfamily of GTPases. GNL1 was …
putative nucleolar GTPase belonging to the HSR1_MMR1 subfamily of GTPases. GNL1 was …
GNL3L is a Nucleo-Cytoplasmic shuttling Protein: Role in cell cycle regulation
IJ Thoompumkal, MRK Subba Rao, A Kumaraswamy… - PLoS one, 2015 - journals.plos.org
GNL3L is an evolutionarily conserved high molecular weight GTP binding nucleolar protein
belonging to HSR1-MMR1 subfamily of GTPases. The present investigation reveals that …
belonging to HSR1-MMR1 subfamily of GTPases. The present investigation reveals that …
An epigenome-wide association study of inflammatory response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network
Aim: Fenofibrate, a PPAR-α inhibitor used for treating dyslipidemia, has well-documented
anti-inflammatory effects that vary between individuals. While DNA sequence variation …
anti-inflammatory effects that vary between individuals. While DNA sequence variation …
Single nucleotide polymorphisms at the PRR3, ABCF1, and GNL1 genes in the HLA class I region are associated with Graves' ophthalmopathy in a gender-dependent …
Objective To investigate whether a conserved HLA class I region influenced the
development of Graves' ophthalmopathy (GO) in patients with Graves' disease (GD) in a …
development of Graves' ophthalmopathy (GO) in patients with Graves' disease (GD) in a …