Mitochondria, ubiquitous double-membrane-bound organelles, regulate energy production,
support cellular activities, harbor metabolic pathways, and, paradoxically, mediate cell fate …

Simple Summary Type 2 cystatins are a group of small secreted protease inhibitors that
regulate cysteine protease cathepsins and legumain. These enzymes regulate important …

Gastric cancer is one of the most common malignancies. Although some patients benefit
from immunotherapy, the majority of patients have unsatisfactory immunotherapy outcomes …

Gastric cancer (GC) remains a predominant form of malignant tumor globally, necessitating
innovative non-surgical therapeutic approaches. This investigation aimed to delineate the …

Introduction Cancer is a crucial public health problem and one of the leading causes of
death worldwide. Previous studies have suggested that GPX3 may be involved in cancer …

Gastric cancer has been associated with a high incidence and mortality, accompanied by a
poor prognosis. Given the limited therapeutic options to treat gastric cancer, alternative …

Background Gastric cancer is a common malignant tumor of the digestive tract, both
domestically and internationally. It has high incidence and mortality rates, posing a …

Introduction Gastric cancer (GC) is the fifth most common tumor, contributing to the third-
highest number of cancer-related deaths. Hypoxia is a major feature of the tumor …

The pathogenesis of ankylosing spondylitis (AS) remains unclear, and while recent studies
have implicated necroptosis in various autoimmune diseases, an investigation of its …

Background Gamma-aminobutyric acid (GABA) plays an important role in tumorigenesis and
progression. Despite this, the role of Reactome GABA receptor activation (RGRA) on gastric …