Comprehensive review of cardiovascular toxicity of drugs and related agents

P Mladěnka, L Applová, J Patočka… - Medicinal research …, 2018 - Wiley Online Library
Cardiovascular diseases are a leading cause of morbidity and mortality in most developed
countries of the world. Pharmaceuticals, illicit drugs, and toxins can significantly contribute to …

Cyperus rotundus L.: Traditional uses, phytochemistry, and pharmacological activities

AM Peerzada, HH Ali, M Naeem, M Latif… - Journal of …, 2015 - Elsevier
Ethno-pharmacological relevance Cyperus rotundus L.(Cyperaceae) is a medicinal herb
traditionally used to treat various clinical conditions at home such as diarrhea, diabetes …

Multi-organ protective effects of curcumin nanoparticles on drug-induced acute myocardial infarction in rats with type 1 diabetes mellitus

PM Boarescu, I Boarescu, AE Bulboacă, IC Bocșan… - Applied Sciences, 2021 - mdpi.com
The objectives of this study were to investigate the cardio-protective, hepatoprotective and
nephroprotective effects of curcumin nanoparticle (NC) pretreatment compared to …

[HTML][HTML] Umbelliferone prevents isoproterenol-induced myocardial injury by upregulating Nrf2/HO-1 signaling, and attenuating oxidative stress, inflammation, and cell …

OY Althunibat, MS Abduh, MH Abukhalil… - Biomedicine & …, 2022 - Elsevier
The role of oxidative injury and inflammatory response in cardiovascular diseases and heart
failure has been well-acknowledged. This study evaluated the protective effect of …

Molecular understanding of the protective role of natural products on isoproterenol-induced myocardial infarction: A review

ZW Wong, PV Thanikachalam… - Biomedicine & …, 2017 - Elsevier
Modern medicine has been used to treat myocardial infarction, a subset of cardiovascular
diseases, and have been relatively effective but not without adverse effects. Consequently …

Inhibition of Pyruvate kinase M2 (PKM2) by shikonin attenuates isoproterenol-induced acute myocardial infarction via reduction in inflammation, hypoxia, apoptosis …

M Rihan, SS Sharma - Naunyn-Schmiedeberg's Archives of Pharmacology, 2024 - Springer
Myocardial infarction (MI) is a major cause of mortality and disability globally. MI results from
acute or chronic myocardial ischemia characterized by an imbalance of oxygen demand and …

'Ajwa'dates (Phoenix dactylifera L.) extract ameliorates isoproterenol-induced cardiomyopathy through downregulation of oxidative, inflammatory and apoptotic …

M Al-Yahya, M Raish, MS AlSaid, A Ahmad… - Phytomedicine, 2016 - Elsevier
Abstract Background/Purpose Ajwa, a special variety of Saudi Arabian dates (Phoenix
dactylifera L.) is a rich source of nutrients, fibers and bioactive molecules. While previous …

Cardioprotective effect of taxifolin against isoproterenol-induced cardiac injury through decreasing oxidative stress, inflammation, and cell death, and activating Nrf2 …

HM Obeidat, OY Althunibat, MA Alfwuaires… - Biomolecules, 2022 - mdpi.com
Oxidative stress and inflammation are key components in cardiovascular diseases and heart
dysfunction. Herein, we evaluated the protective effects of (+)-taxifolin (TAX), a potent …

Curcumin nanoparticles protect against isoproterenol induced myocardial infarction by alleviating myocardial tissue oxidative stress, electrocardiogram, and biological …

PM Boarescu, I Boarescu, IC Bocșan, RM Pop… - Molecules, 2019 - mdpi.com
Curcumin from Curcuma longa is a nutraceutical compound reported to possess strong
antioxidant activity that makes it a candidate for use in counteracting oxidative stress …

Thymoquinone protects against cardiac mitochondrial DNA loss, oxidative stress, inflammation and apoptosis in isoproterenol-induced myocardial infarction in rats

AA Khalifa, RM Rashad, WF El-Hadidy - Heliyon, 2021 - cell.com
Introduction Myocardial infarction (MI) is an ischemic life-threatening disease with
exaggerated oxidative stress state that vigorously damages the cardiomyocyte membrane …