Metabolic syndrome (MetS) forms a cluster of metabolic dysregulations including insulin
resistance, atherogenic dyslipidemia, central obesity, and hypertension. The pathogenesis …

Obesity is a complex, chronic disease and global public health challenge. Characterized by
excessive fat accumulation in the body, obesity sharply increases the risk of several …

Obesity is a state of low-grade chronic inflammation that causes multiple metabolic
diseases. During obesity, signalling via cytokines of the TNF family mediate cell death and …

Chronic low-grade inflammation in adipose tissue (AT) is a hallmark of obesity and
contributes to various metabolic disorders, such as type 2 diabetes and cardiovascular …

Even though type 2 diabetes mellitus (T2DM) represents a worldwide chronic health issue
that affects about 462 million people, specific underlying determinants of insulin resistance …

Metabolic reprogramming is involved in the pathogenesis of not only cancers but also
neurodegenerative diseases, cardiovascular diseases, and infectious diseases. With the …

The occurrence of obesity has increased across the whole world. Many epidemiological
studies have indicated that obesity strongly contributes to the development of cancer …

Squamous cell carcinomas are triggered by marked elevation of RAS–MAPK signalling and
progression from benign papilloma to invasive malignancy,,–. At tumour–stromal interfaces …

Childhood obesity is a leading public health problem worldwide, as it is increasingly
prevalent and therefore responsible for serious obesity-related comorbidities, not only in …

Thyroid cancer (TC) is the most common endocrine malignancy worldwide and its incidence
has increased dramatically in recent years. In parallel, the prevalence of overweight and …