Cancer across the tree of life: cooperation and cheating in multicellularity

CA Aktipis, AM Boddy, G Jansen… - … of the Royal …, 2015 - royalsocietypublishing.org
Multicellularity is characterized by cooperation among cells for the development,
maintenance and reproduction of the multicellular organism. Cancer can be viewed as …

Molecular aspects of regeneration mechanisms in holothurians

IY Dolmatov - Genes, 2021 - mdpi.com
Holothurians, or sea cucumbers, belong to the phylum Echinodermata. They show good
regenerative abilities. The present review provides an analysis of available data on the …

Echinoderms: potential model systems for studies on muscle regeneration

JE García-Arrarás, IY Dolmatov - Current pharmaceutical …, 2010 - ingentaconnect.com
Organisms of the phylum Echinodermata show some of the most impressive regenerative
feats within the animal kingdom. Following injury or self-induced autotomy, species in this …

Gut regeneration in holothurians: a snapshot of recent developments

VS Mashanov, JE García-Arrarás - The biological bulletin, 2011 - journals.uchicago.edu
Visceral regeneration in sea cucumbers has been studied since early last century; however,
it is only within the last 15 years that real progress has been made in understanding the …

RNA-Seq Reveals Dynamic Changes of Gene Expression in Key Stages of Intestine Regeneration in the Sea Cucumber Apostichopus japonicas

L Sun, H Yang, M Chen, D Ma, C Lin - PloS one, 2013 - journals.plos.org
Background Sea cucumbers (Holothuroidea; Echinodermata) have the capacity to
regenerate lost tissues and organs. Although the histological and cytological aspects of …

The Eupentacta fraudatrix transcriptome provides insights into regulation of cell transdifferentiation

AV Boyko, AS Girich, ES Tkacheva, IY Dolmatov - Scientific reports, 2020 - nature.com
The holothurian Eupentacta fraudatrix is a unique organism for studying regeneration
mechanisms. Moreover, E. fraudatrix can quickly restore parts of its body and entire organ …

[HTML][HTML] Matrix metalloproteinases and tissue inhibitors of metalloproteinases in echinoderms: Structure and possible functions

IY Dolmatov, VA Nizhnichenko, LS Dolmatova - Cells, 2021 - mdpi.com
Echinoderms are one of the most ancient groups of invertebrates. The study of their
genomes has made it possible to conclude that these animals have a wide variety of matrix …

Cell dedifferentiation and epithelial to mesenchymal transitions during intestinal regeneration in H. glaberrima

JE García-Arrarás, G Valentín-Tirado, JE Flores… - BMC Developmental …, 2011 - Springer
Background Determining the type and source of cells involved in regenerative processes
has been one of the most important goals of researchers in the field of regeneration biology …

Expression of pluripotency factors in echinoderm regeneration

VS Mashanov, OR Zueva, JE García-Arrarás - Cell and tissue research, 2015 - Springer
Cell dedifferentiation is an integral component of post-traumatic regeneration in
echinoderms. As dedifferentiated cells become multipotent, we asked if this spontaneous …

Radial glial cells play a key role in echinoderm neural regeneration

VS Mashanov, OR Zueva, JE García-Arrarás - BMC biology, 2013 - Springer
Background Unlike the mammalian central nervous system (CNS), the CNS of echinoderms
is capable of fast and efficient regeneration following injury and constitutes one of the most …