Cardiovascular disease remains the principal cause of death and disability among patients
with diabetes mellitus. Diabetes mellitus exacerbates mechanisms underlying …

Endothelial dysfunction is one of the initial steps in the pathogenesis of atherosclerosis and
development of cardiovascular disease in patients with diabetes mellitus. Several risk …

NADPH oxidases (NOX) are enzyme complexes that have received much attention as key
molecules in the development of vascular dysfunction. NOX have the primary function of …

OBJECTIVE In recent years, some studies have indicated that a novel marker described as
the stress hyperglycemia ratio (SHR) can reflect true acute hyperglycemic status and is …

The cardiovascular disease continuum begins with risk factors such as diabetes mellitus
(DM), progresses to vasculopathy and myocardial dysfunction, and finally ends with …

Cardiovascular diseases (CVDs) in the course of atherosclerosis are one of the most critical
public health problems in the world. Endothelial cells synthesize numerous biologically …

Low-grade inflammation is a characteristic of the obese state, and adipose tissue releases
many inflammatory mediators. The source of these mediators within adipose tissue is not …

Diabetes-specific microvascular disease is a leading cause of blindness, renal failure and
nerve damage, and diabetes-accelerated atherosclerosis leads to increased risk of …

Postprandial glucose, together with related hyperinsulinemia and lipidaemia, has been
implicated in the development of chronic metabolic diseases like obesity, type 2 diabetes …

Endothelial dysfunction is characterized by a shift of the actions of the endothelium toward
reduced vasodilation, a proinflammatory state, and prothrombic properties. It is associated …