Protective mechanism of humanin against oxidative stress in aging-related cardiovascular diseases
H Cai, Y Liu, H Men, Y Zheng - Frontiers in Endocrinology, 2021 - frontiersin.org
Physiological reactive oxygen species (ROS) are important regulators of intercellular signal
transduction. Oxidative and antioxidation systems maintain a dynamic balance under …
transduction. Oxidative and antioxidation systems maintain a dynamic balance under …
Interplay between lipid metabolism, lipid droplets, and DNA virus infections
MA Farías, B Diethelm-Varela, AJ Navarro, AM Kalergis… - Cells, 2022 - mdpi.com
Lipid droplets (LDs) are cellular organelles rich in neutral lipids such as triglycerides and
cholesterol esters that are coated by a phospholipid monolayer and associated proteins …
cholesterol esters that are coated by a phospholipid monolayer and associated proteins …
Resistance evolution against host-directed antiviral agents: Buffalopox virus switches to use p38-ϒ under long-term selective pressure of an inhibitor targeting p38-α
Y Chander, R Kumar, A Verma… - Molecular biology …, 2022 - academic.oup.com
Host-dependency factors have increasingly been targeted to minimize antiviral drug
resistance. In this study, we have demonstrated that inhibition of p38 mitogen-activated …
resistance. In this study, we have demonstrated that inhibition of p38 mitogen-activated …
Identification of Cell Types and Transcriptome Landscapes of Porcine Epidemic Diarrhea Virus–Infected Porcine Small Intestine Using Single-Cell RNA Sequencing
B Fan, J Zhou, Y Zhao, X Zhu, M Zhu… - The Journal of …, 2023 - journals.aai.org
Swine coronavirus–porcine epidemic diarrhea virus (PEDV) with specific susceptibility to
pigs has existed for decades, and recurrent epidemics caused by mutant strains have swept …
pigs has existed for decades, and recurrent epidemics caused by mutant strains have swept …
S-adenosylmethionine-dependent methyltransferase inhibitor DZNep blocks transcription and translation of SARS-CoV-2 genome with a low tendency to select for …
R Kumar, N Khandelwal, Y Chander, H Nagori… - Antiviral research, 2022 - Elsevier
We report the in vitro antiviral activity of DZNep (3-Deazaneplanocin A; an inhibitor of S-
adenosylmethionine-dependent methyltransferase) against SARS-CoV-2, besides …
adenosylmethionine-dependent methyltransferase) against SARS-CoV-2, besides …
Hyperoside inhibits EHV-8 infection via alleviating oxidative stress and IFN production through activating JNK/Keap1/Nrf2/HO-1 signaling pathways
T Wang, L Hu, R Li, H Ren, S Li, Q Sun, X Ding… - Journal of …, 2024 - Am Soc Microbiol
ABSTRACT Equine herpesvirus type 8 (EHV-8) causes abortion and respiratory disease in
horses and donkeys, leading to serious economic losses in the global equine industry …
horses and donkeys, leading to serious economic losses in the global equine industry …
MiR-103a-3p promotes Zika virus replication by targeting OTU Deubiquitinase 4 to activate p38 mitogen-activated protein kinase signaling pathway
H Ye, L Kang, X Yan, S Li, Y Huang, R Mu… - Frontiers in …, 2022 - frontiersin.org
Background MicroRNAs (miRNAs) play critical roles in regulating virus infection and
replication. However, the mechanism by which miRNA regulates Zika virus (ZIKV) replication …
replication. However, the mechanism by which miRNA regulates Zika virus (ZIKV) replication …
Cardamonin as a p38 MAPK signaling pathway activator inhibits human coronavirus OC43 infection in human lung cells
A natural chalcone, cardamonin (2′, 4′-dihydroxy-6′-methoxychalcone; CDN) was
isolated from the seeds of Alpinia katsumadai Hayata, which has been traditionally used to …
isolated from the seeds of Alpinia katsumadai Hayata, which has been traditionally used to …
Tannic Acid Suppresses HBV Replication via the Regulation of NF-κB, MAPKs, and Autophagy in HepG2. 2.15 Cells
X Wang, B Hu, H Hu, S Zhou, M Yin… - Journal of Agricultural …, 2023 - ACS Publications
Hepatitis B virus (HBV) infection is a serious global health problem that threatens the health
of human. Tannic acid (TA), a natural polyphenol in foods, fruits, and plants, exhibits a …
of human. Tannic acid (TA), a natural polyphenol in foods, fruits, and plants, exhibits a …
[HTML][HTML] Duck Tembusu virus infection activates the MKK3/6-p38 MAPK signaling pathway to promote virus replication
Y Cheng, L Jiao, J Chen, P Chen, F Zhou, J Zhang… - Veterinary …, 2024 - Elsevier
Duck Tembusu virus (DTMUV) infection poses a serious threat to ducks, chickens, and
geese, causing a range of detrimental effects, including reduced egg production, growth …
geese, causing a range of detrimental effects, including reduced egg production, growth …