As warned by Sir Alexander Fleming in his Nobel Prize address:“the use of antimicrobials
can, and will, lead to resistance”. Antimicrobial resistance (AMR) has recently increased due …

Pharmacokinetic/pharmacodynamic (PK/PD) analysis has proved to be very useful to
establish rational dosage regimens of antimicrobial agents in human and veterinary …

Introduction The aim of this international project was to establish a species-specific Clinical
Breakpoint for interpretation of Antimicrobial Susceptibility Testing of benzylpenicillin (BP) in …

Pharmacokinetic/pharmacodynamic (PK/PD) integration models are used to investigate the
antimicrobial activity characteristics of drugs targeting pathogenic bacteria through …

Florfenicol is a member of the phenicol group, a broad-spectrum antibacterial agent. It has
been used for a long time in veterinary medicine, but there are some factors regarding its …

Porcine respiratory disease complex (PRDC) has been a major animal health, welfare, and
economic problem in Hungary; therefore, great emphasis should be put on both the …

Simple Summary The pharmacokinetic/pharmacodynamic studies report the use of
enrofloxacin at higher doses than 10 mg/kg in fish. Pharmacokinetic data for increasing …

The dosage of colistin for the treatment of enteric E. coli in animals necessitates considering
the heteroresistant (HR) nature of the targeted inoculum, described by the presence of a …

Cefquinome is widely used to treat respiratory tract diseases of swine. While extra-label
dosages of cefquinome could improve clinical efficacy, they might lead to excessively high …

The aim of the study was to investigate the plasma and muscle pharmacokinetic of
enrofloxacin (ENR) and its active metabolite ciprofloxacin (CIP) in Nile tilapia (Oreochromis …