Markers of liver regeneration—the role of growth factors and cytokines: a systematic review

K Hoffmann, AJ Nagel, K Tanabe, J Fuchs, K Dehlke… - BMC surgery, 2020 - Springer
Background Post-hepatectomy liver failure contributes significantly to postoperative mortality
after liver resection. The prediction of the individual risk for liver failure is challenging. This …

[HTML][HTML] Molecular pathways of liver regeneration: A comprehensive review

YV Kiseleva, SZ Antonyan, TS Zharikova… - World Journal of …, 2021 - ncbi.nlm.nih.gov
The liver is a unique parenchymal organ with a regenerative capacity allowing it to restore
up to 70% of its volume. Although knowledge of this phenomenon dates back to Greek …

[HTML][HTML] Berberine improves DSS-induced colitis in mice by modulating the fecal-bacteria-related bile acid metabolism

X Sun, Y Zhang, G Cheng, T Zhu, Z Zhang… - Biomedicine & …, 2023 - Elsevier
Ulcerative colitis (UC) has been confirmed as a disease with a high incidence and low cure
rate worldwide. In severe cases, UC can develop into colon cancer. Modern research has …

Molecular pathways governing the termination of liver regeneration

LR de Haan, RF van Golen, M Heger, M Michel - Pharmacological reviews, 2024 - Elsevier
The liver has the unique capacity to regenerate, and up to 70% of the liver can be removed
without detrimental consequences to the organism. Liver regeneration is a complex process …

Interleukin‐33 facilitates liver regeneration through serotonin‐involved gut‐liver axis

Y Wen, C Emontzpohl, L Xu, CL Atkins, JM Jeong… - Hepatology, 2023 - journals.lww.com
Conclusions: Our study identified that IL‐33 is pro‐regenerative in a noninjurious model of
liver resection. The underlying mechanism involved IL‐33/ST2‐induced increase of …

[HTML][HTML] Understanding the hepatoxicity of inorganic mercury through guts: Perturbance to gut microbiota, alteration of gut-liver axis related metabolites and damage to …

X Lin, W Zhang, L He, H Xie, B Feng, H Zhu… - Ecotoxicology and …, 2021 - Elsevier
Mercury (Hg) brings adverse effects to the environment and human beings and inorganic
mercury (IHg) is a typical hepatic toxin. This work studied the impacts of IHg on gut microbes …

Liver regeneration observed across the different classes of vertebrates from an evolutionary perspective

B Delgado-Coello - Heliyon, 2021 - cell.com
The liver is a key organ that performs diverse functions such as metabolic processing of
nutrients or disposal of dangerous substances (xenobiotics). Accordingly, it seems to be …

Overexpression of miR-125a-5p inhibits hepatocyte proliferation through the STAT3 regulation in vivo and in vitro

C Zhang, Y Zhao, Q Wang, J Qin, B Ye, C Xu… - International journal of …, 2022 - mdpi.com
microRNAs (miRNAs) are critically involved in liver regeneration (LR). miR-125a-5p (miR-
125a) is a tumor-suppressing miRNA, but its role in LR has not been studied. Our previous …

Bile acids as novel enhancers of CNS targeting antitumor drugs: A comprehensive review

M Gvoic, S Vukmirovic, H Al-Salami… - Pharmaceutical …, 2021 - Taylor & Francis
Despite a relatively low prevalence of primary brain tumors, they continuously attract
scientific interest because of the complexity of their treatment due to their location behind the …

Amygdalin (vitamin B17) pretreatment attenuates experimentally induced acute autoimmune hepatitis through reduction of CD4+ cell infiltration

WM Elsaed - Annals of Anatomy-Anatomischer Anzeiger, 2019 - Elsevier
Background Autoimmune hepatitis (AIH) is an immune-mediated inflammation of the liver
characterized by disorganized hepatic parenchyma and inflammatory cell infiltration …