A. actinomycetemcomitans has clearly adapted well to its environs; its armamentarium of
virulence factors (Table 2) ensures its survival in the oral cavity and enables it to promote …

Abstract β-Lactamases enable resistance to almost all β-lactam antibiotics. Pioneering work
revealed that acyclic boronic acids can act as 'transition state analogue'inhibitors of …

The level of genetic variation of human immunodeficiency virus type 1 (HIV-1), a member of
the lentivirus genus of the Retroviridae family, is high relative to that of retroviruses in some …

Targeted killing of pathogenic bacteria without harming beneficial members of host
microbiota holds promise as a strategy to cure disease and limit both antimicrobial-related …

Spent culture supernatants from both Aeromonas hydrophila and Aeromonas salmonicida
activate a range of biosensors responsive to N-acylhomoserine lactones (AHLs). The genes …

The regulatory programme of multicellular behaviour in Salmonella typhimurium is
determined by mutations in the agfD promoter. AgfD has already been identified to regulate …

Strains of Escherichia coli were constructed and evaluated that synthesized cis, cis‐muconic
acid from d‐glucose under fed‐batch fermentor conditions. Chemical hydrogenation of the …

The OxyS regulatory RNA integrates the adaptive response to hydrogen peroxide with other
cellular stress responses and protects against DNA damage. Among the OxyS targets is the …

The ability of bacteria to acquire and disseminate heterologous genes has been a major
factor in the development of multiple drug resistance. A gene, intI4, was identified that …

1-Amino-cyclopropane-1-carboxylate synthase (ACS, EC 4.4. 1.14) is the key enzyme in the
ethylene biosynthetic pathway in plants. The completion of the Arabidopsis genome …