The pros and cons of mesenchymal stem cell-based therapies

A Musiał-Wysocka, M Kot, M Majka - Cell transplantation, 2019 - journals.sagepub.com
The need to search for new, alternative treatments for various diseases has prompted
scientists and physicians to focus their attention on regenerative medicine and broadly …

Multifunctional coatings to simultaneously promote osseointegration and prevent infection of orthopaedic implants

J Raphel, M Holodniy, SB Goodman, SC Heilshorn - Biomaterials, 2016 - Elsevier
The two leading causes of failure for joint arthroplasty prostheses are aseptic loosening and
periprosthetic joint infection. With the number of primary and revision joint replacement …

Cryogel/hydrogel biomaterials and acupuncture combined to promote diabetic skin wound healing through immunomodulation

TY Chen, TK Wen, NT Dai, S Hsu - Biomaterials, 2021 - Elsevier
Unhealed chronic wounds often deteriorate into multiple infection with several kinds of
bacteria and excessive proteolytic wound exudate and remains one of the common …

Mesenchymal Stem Cells Derived from Dental Tissues vs. Those from Other Sources: Their Biology and Role in Regenerative Medicine

GTJ Huang, S Gronthos, S Shi - Journal of dental research, 2009 - journals.sagepub.com
To date, 5 different human dental stem/progenitor cells have been isolated and
characterized: dental pulp stem cells (DPSCs), stem cells from exfoliated deciduous teeth …

Mesenchymal stem cells migration homing and tracking

A Sohni, CM Verfaillie - Stem cells international, 2013 - Wiley Online Library
In this review, we discuss the migration and homing ability of mesenchymal stem cells
(MSCs) and MSC‐like cells and factors influencing this. We also discuss studies related to …

Concise review: mesenchymal stem cells: their phenotype, differentiation capacity, immunological features, and potential for homing

G Chamberlain, J Fox, B Ashton, J Middleton - Stem cells, 2007 - academic.oup.com
MSCs are nonhematopoietic stromal cells that are capable of differentiating into, and
contribute to the regeneration of, mesenchymal tissues such as bone, cartilage, muscle …

How do stem cells find their way home?

T Lapidot, A Dar, O Kollet - Blood, 2005 - ashpublications.org
Migration of hematopoietic stem cells through the blood, across the endothelial vasculature
to different organs and to their bone marrow (BM) niches, requires active navigation, a …

Stromal cell–derived factor 1/CXCR4 signaling is critical for the recruitment of mesenchymal stem cells to the fracture site during skeletal repair in a mouse model

T Kitaori, H Ito, EM Schwarz, R Tsutsumi… - … : Official Journal of …, 2009 - Wiley Online Library
Objective Stromal cell–derived factor 1 (SDF‐1; CXCL12/pre–B cell growth‐stimulating
factor) is a dominant chemokine in bone marrow and is known to be involved in …

The stem cell niches in bone

T Yin, L Li - The Journal of clinical investigation, 2006 - Am Soc Clin Investig
The stem cell niche is composed of a specialized population of cells that plays an essential
role in regulating adult stem cell self-renewal and differentiation. In adults, osteoblasts …

Chemokines in physiological and pathological bone remodeling

LJ Brylka, T Schinke - Frontiers in immunology, 2019 - frontiersin.org
The bone matrix is constantly remodeled by bone-resorbing osteoclasts and bone-forming
osteoblasts. These two cell types are fundamentally different in terms of progenitor cells …