Wearable and implantable devices for cardiovascular healthcare: from monitoring to therapy based on flexible and stretchable electronics

YJ Hong, H Jeong, KW Cho, N Lu… - Advanced Functional …, 2019 - Wiley Online Library
Cardiovascular disease is the leading cause of death and has dramatically increased in
recent years. Continuous cardiac monitoring is particularly important for early diagnosis and …

Stem cell therapy in heart diseases–cell types, mechanisms and improvement strategies

P Müller, H Lemcke, R David - Cellular Physiology and Biochemistry, 2018 - karger.com
A large number of clinical trials have shown stem cell therapy to be a promising therapeutic
approach for the treatment of cardiovascular diseases. Since the first transplantation into …

Cardiac recovery via extended cell-free delivery of extracellular vesicles secreted by cardiomyocytes derived from induced pluripotent stem cells

B Liu, BW Lee, K Nakanishi, A Villasante… - Nature biomedical …, 2018 - nature.com
The ability of extracellular vesicles (EVs) to regulate a broad range of cellular processes has
recently been exploited for the treatment of diseases. For example, EVs secreted by …

In situ-forming injectable hydrogels for regenerative medicine

JA Yang, J Yeom, BW Hwang, AS Hoffman… - Progress in polymer …, 2014 - Elsevier
Regenerative medicine involves interdisciplinary biomimetic approaches for cell therapy
and tissue regeneration, employing the triad of cells, signals, and/or scaffolds. Remarkably …

Safety and immunological effects of mesenchymal stem cell transplantation in patients with multiple sclerosis and amyotrophic lateral sclerosis

D Karussis, C Karageorgiou… - Archives of …, 2010 - jamanetwork.com
Objective To evaluate the feasibility, safety, and immunological effects of intrathecal and
intravenous administration of autologous mesenchymal stem cells (MSCs)(also …

Secretion of angiogenic and antiapoptotic factors by human adipose stromal cells

J Rehman, D Traktuev, J Li, S Merfeld-Clauss… - Circulation, 2004 - Am Heart Assoc
Background—The delivery of autologous cells to increase angiogenesis is emerging as a
treatment option for patients with cardiovascular disease but may be limited by the …

Mesenchymal stem cells: clinical applications and biological characterization

FP Barry, JM Murphy - The international journal of biochemistry & cell …, 2004 - Elsevier
Mesenchymal stem cells (MSCs) have been isolated from bone marrow, periosteum,
trabecular bone, adipose tissue, synovium, skeletal muscle and deciduous teeth. These …

Intelligent image-based deformation-assisted cell sorting with molecular specificity

AA Nawaz, M Urbanska, M Herbig, M Nötzel, M Kräter… - Nature …, 2020 - nature.com
Although label-free cell sorting is desirable for providing pristine cells for further analysis or
use, current approaches lack molecular specificity and speed. Here, we combine real-time …

Plasticity of adult stem cells

AJ Wagers, IL Weissman - Cell, 2004 - cell.com
Recent years have seen much excitement over the possibility that adult mammalian stem
cells may be capable of differentiating across tissue lineage boundaries, and as such may …

Double‐edged sword of mesenchymal stem cells: cancer‐promoting versus therapeutic potential

HY Lee, IS Hong - Cancer science, 2017 - Wiley Online Library
Mesenchymal stem cells (MSCs) derived from adipose tissue, bone marrow, cord blood, and
other tissues, have recently attracted much attention as potential therapeutic agents in …