[HTML][HTML] Neuropathic pain: from mechanisms to treatment

NB Finnerup, R Kuner, TS Jensen - Physiological reviews, 2020 - journals.physiology.org
Neuropathic pain caused by a lesion or disease of the somatosensory nervous system is a
common chronic pain condition with major impact on quality of life. Examples include …

Structural plasticity and reorganisation in chronic pain

R Kuner, H Flor - Nature Reviews Neuroscience, 2017 - nature.com
Chronic pain is not simply a temporal continuum of acute pain. Studies on functional
plasticity in neural circuits of pain have provided mechanistic insights and linked various …

[HTML][HTML] Cellular circuits in the brain and their modulation in acute and chronic pain

R Kuner, T Kuner - Physiological reviews, 2020 - journals.physiology.org
Chronic, pathological pain remains a global health problem and a challenge to basic and
clinical sciences. A major obstacle to preventing, treating, or reverting chronic pain has been …

Spared nerve injury causes sexually dimorphic mechanical allodynia and differential gene expression in spinal cords and dorsal root ganglia in rats

FHG Ahlström, K Mätlik, H Viisanen, KJ Blomqvist… - Molecular …, 2021 - Springer
Neuropathic pain is more prevalent in women. However, females are under-represented in
animal experiments, and the mechanisms of sex differences remain inadequately …

Facilitation of neuropathic pain by the NPY Y1 receptor-expressing subpopulation of excitatory interneurons in the dorsal horn

TS Nelson, W Fu, RR Donahue, GF Corder, T Hökfelt… - Scientific reports, 2019 - nature.com
Endogenous neuropeptide Y (NPY) exerts long-lasting spinal inhibitory control of
neuropathic pain, but its mechanism of action is complicated by the expression of its …

Sex differences in central nervous system plasticity and pain in experimental autoimmune encephalomyelitis

A Catuneanu, JW Paylor, I Winship, F Colbourne… - Pain, 2019 - journals.lww.com
Multiple sclerosis (MS) is a neurodegenerative autoimmune disease with many known
structural and functional changes in the central nervous system. A well-recognized, but …

Effects of peripheral nerve injury on parvalbumin expression in adult rat dorsal root ganglion neurons

T Medici, PJ Shortland - BMC neuroscience, 2015 - Springer
Background Parvalbumin (PV) is a calcium binding protein that identifies a subpopulation of
proprioceptive dorsal root ganglion (DRG) neurons. Calcitonin gene-related peptide (CGRP) …

[图书][B] Quick reference neuroscience for rehabilitation professionals: The essential neurologic principles underlying rehabilitation practice

SA Gutman - 2024 - taylorfrancis.com
" Quick Reference NeuroScience for Rehabilitation Professionals: The Essential Neurologic
Principles Underlying Rehabilitation Practice, Third Edition" is a user-friendly …

Involvement of neuropeptide Y in post-incisional nociception in rats

S Gupta, M Gautam, P Prasoon, R Kumar… - Annals of …, 2019 - karger.com
Background: Neuropeptide Y (NPY) is abundantly distributed in the mammalian nervous
system. Its role in nociception arising from inflammatory and neuropathic pain conditions has …

Voltage-gated calcium channels in the afferent pain pathway

L Ferron, GW Zamponi - Voltage-Gated Calcium Channels, 2022 - Springer
Voltage-gated calcium channels are important mediators of signal transduction in the
primary afferent pain pathway. In rodents, T-type calcium channels regulate the excitability of …