Myocardial infarction (MI) is the irreversible death of cardiomyocyte secondary to prolonged
lack of oxygen or fresh blood supply. Historically considered as merely cardiomyocyte …

Acute myocardial infarction (AMI) and the heart failure (HF) that often follows are among the
leading causes of death and disability worldwide. As such, new treatments are needed to …

Anthracyclines, such as doxorubicin, are effective chemotherapeutic agents for the treatment
of cancer, but their clinical use is associated with severe and potentially life-threatening …

Cadmium (Cd) is one of the most toxic metals without biological function, and its
accumulation in living organisms has been reported. The kidney is a target organ in Cd …

Neurons and glia maintain central nervous system (CNS) homeostasis through diverse
mechanisms of intra-and intercellular signaling. Some of these interactions include the …

Acute kidney injury is a common clinical disorder and one of the major causes of morbidity
and mortality in the postoperative period. In this study, the safety and efficacy of autologous …

There is a steadily growing interest in the use of mitochondria as therapeutic agents. The
use of mitochondria derived from mesenchymal stem/stromal cells (MSCs) for therapeutic …

Background Mitochondria are essential organelles that provide energy for cellular functions,
participate in cellular signaling and growth, and facilitate cell death. Based on their …

Mitochondrial damage is a critical driver in myocardial ischemia-reperfusion (I/R) injury and
can be alleviated via the mitochondrial transplantation. The efficiency of mitochondrial …

Abstract Background Mitochondrial transplantation (MTx) is an emerging but poorly
understood technology with the potential to mitigate severe ischemia–reperfusion injuries …