Recurrent protein folding motifs include various types of helical bundles formed by α-helices
that supercoil around each other. While specific patterns of amino acid residues (heptad …

This study aims to the investigation of the advantages of designing new proteins presume
upon a 'bias' sequence of amino acids, based on the reversed sequence of parent proteins …

Simple Summary Reversion of the wild-type protein sequences of single transmembrane
melanocortin accessory protein families (MRAP2) in mice and zebrafish created novel …

Neuroprotective antioxidants, especially peptide-based antioxidants, are effective against
oxidative stress in neurodegenerative disorders. In this study, we measured the …

One natural antimicrobial peptide (EpVP2a, Eumenes pomiformis Venom Peptide 2a) found
in the venom of a potter wasp (Eumenes pomiformis) and six analogs were synthesized and …

Sequence patterns of charge, hydrophobicity, hydrogen bonding, and other amino acid
physicochemical properties contribute to mechanisms of protein folding, but how sequence …

We use all‐atom modeling and advanced‐sampling molecular dynamics simulations to
investigate quantitatively the effect of peptide bond directionality on the equilibrium …

This gives a general overview of the complex nature of proteins and how their basic,
secondary, and tertiary structures affect both their structure and function. It opens by …