Simple Summary Connexin hemichannels are formed by connexin protein family members,
and connect cytosol and extracellular milium. The function of connexin hemichannels cannot …

Cardiac connexin-43 (Cx43) creates gap junction channels (GJCs) at intercellular contacts
and hemi-channels (HCs) at the peri-junctional plasma membrane and sarcolemmal …

Antibody-based strategies have been attempted to antagonize early cytokines of sepsis, but
not yet been tried to target inducible late-acting mediators. Here, we report that the …

Connexins, in particular connexin 43 (Cx43), function as gap junction channels (GJCs) and
hemichannels (HCs). Only recently, specific tools have been developed to study their …

The number of skeletal muscle injuries derived from myopathies, exercise, and trauma, is
growing due to increasing sports activities in normal life of people. Skeletal muscle has a …

Background Emerging evidence indicates an excess risk of late occurring cardiovascular
diseases, especially atherosclerosis, after thoracic cancer radiotherapy. Ionizing radiation …

Uveitis is a complex ocular inflammatory disease often accompanied by bacterial or viral
infections (infectious uveitis) or underlying autoimmune diseases (non-infectious uveitis) …

Introduction: Chronic inflammatory diseases, including retinal diseases that are a major
cause of vision loss, are associated with activation of the nucleotide-binding domain and …

Connexin 43 (Cx43) widely exists in all components of the neurovascular unit (NVU) and is
a constituent of gap junctions and hemichannels. In physiological states, gap junctions are …

Recent studies have helped to increase the understanding of the function of Connexin-43
(Cx43) in macrophages (Mφ). The various roles of Cx43 in Mφs range from migration …