Pyrazole aminopyrimidine derivatives as LRRK2 modulators

C Baker-Glenn, DJ Burdick, M Chambers… - US Patent …, 2014 - Google Patents
7,166.599 B2 1/2007 Bornemann et al. 7,173,028 B2 2/2007 Dahmann et al. 7,235,561 B2
6/2007 Brumby et al. 7,235,562 B2 6, 2007 Kath et al. 7,241,769 B2 7/2007 Stadtmueller et …

Phenylaminopyrimidine amide autophagy inhibitors and methods of use thereof

DL Flynn, YM Ahn, T Caldwell, L Vogeti - US Patent 11,530,206, 2022 - Google Patents
2021-10-27 Assigned to DECIPHERA PHARMACEUTICALS, LLC reassignment
DECIPHERA PHARMACEUTICALS, LLC ASSIGNMENT OF ASSIGNORS INTEREST (SEE …

Heteroarylaminopyrimidine amide autophagy inhibitors and methods of use thereof

DL Flynn, YM Ahn, T Caldwell, L Vogeti - US Patent 11,518,758, 2022 - Google Patents
2021-10-27 Assigned to DECIPHERA PHARMACEUTICALS, LLC reassignment
DECIPHERA PHARMACEUTICALS, LLC ASSIGNMENT OF ASSIGNORS INTEREST (SEE …

Aminopyrimidine derivatives as LRRK2 modulators

C Baker-Glenn, M Chambers, BK Chan… - US Patent …, 2014 - Google Patents
Neurodegenerative diseases such as Parkinson's disease, Lewy body dementia and
Huntington's disease affect mil lions of individuals. Parkinson's disease is a chronic, progres …

Aminopyrimidine derivatives as LRRK2 modulators

C Baker-Glenn, DJ Burdick, M Chambers… - US Patent …, 2014 - Google Patents
Specific Compounds of formula I: or pharmaceutically acceptable salts thereof, wherein m,
X, RRRRR and R7 are as defined herein. Also disclosed are methods of making the com …

Aminopyrimidine derivatives as LRRK2 modulators

C Baker-Glenn, DJ Burdick, M Chambers… - US Patent …, 2014 - Google Patents
Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n. X,
RRRRR and R7 are as defined herein. Also disclosed are methods of making the com …

Aminopyrimidine derivatives as LRRK2 modulators

C Baker-Glenn, M Chambers, BK Chan… - US Patent …, 2014 - Google Patents
Neurodegenerative diseases such as Parkinson's disease, Lewy body dementia and
Huntington's disease affect mil lions of individuals. Parkinson's disease is a chronic, progres …

Bicyclic pyrazole LRRK2 small molecule inhibitors

C Baker-Glenn, BK Chan, J Dotson, A Estrada… - US Patent …, 2015 - Google Patents
US9212186B2 - Bicyclic pyrazole LRRK2 small molecule inhibitors - Google Patents
US9212186B2 - Bicyclic pyrazole LRRK2 small molecule inhibitors - Google Patents Bicyclic …

Compounds inhibiting leucine-rich repeat kinase enzyme activity

M Miller, K Basu, D DeMong, J Scott, W Li… - US Patent …, 2016 - Google Patents
The present invention is directed to indazole compounds which are potent inhibitors of
LRRK2 kinase and useful in the treatment or prevention of diseases in which the LRRK2 …

Aminopyrimidine amide autophagy inhibitors and methods of use thereof

DL Flynn, YM Ahn, T Caldwell, L Vogeti - US Patent 11,590,134, 2023 - Google Patents
2021-10-27 Assigned to DECIPHERA PHARMACEUTICALS, LLC reassignment
DECIPHERA PHARMACEUTICALS, LLC ASSIGNMENT OF ASSIGNORS INTEREST (SEE …