Epithelial ovarian cancer, which comprises several histologic types and grades, is the most
lethal cancer among women in the United States. In this review, we summarize recent …

Ovarian cancer is the deadliest of gynecological malignancies with approximately 49% of
women surviving 5 years after initial diagnosis. The standard of care for ovarian cancer …

The validation of prognostic biomarkers in large independent patient cohorts is a major
bottleneck in ovarian cancer research. We implemented an online tool to assess the …

Purpose: Dysregulation of cell cycle control, in particular G1-S-phase transition, is implicated
in the pathogenesis of most human cancers, including epithelial ovarian cancer (EOC) …

Background It has been widely realized that pathways rather than individual genes govern
the course of carcinogenesis. Therefore, discovering driver pathways is becoming an …

Endometriosis is defined as the presence of ectopic endometrial tissue outside of the uterine
cavity, most commonly in the ovaries and peritoneum. It is a complex disease that is …

MicroRNAs (miRNAs) are small non‐coding RNAs that exert a regulatory effect post‐
transcriptionally by binding target mRNAs and inhibiting gene translation. miRNA …

Tumour stage, residual disease after initial surgery, histological type and tumour grade are
the most important clinical-pathological factors related to the clinical outcome of patients with …

OBJECTIVE.: Notch1 signaling is active in ovarian cancer and is a promising pathway for
new therapies in ovarian cancer. We have previously detected high Notch1 expression in …

Cyclin D1 and c-Myc are key participants in the cell-cycle pathway, in which aberrancies
have been associated with malignant transformation. To date, data on the relationship of …