The method comprises providing a lancing device compris ing a penetrating member (68)
driver having a position sensor (74) and a processor (60) that can determine the relative …

US PATENT DOCUMENTS the microneedles to penetrate the biological barrier, other
2,893,392 A 7/1959 Wagner et al. than the Simply direct pressure of the microneedle …

Microneedle devices are provided for transport of therapeutic and biological molecules
across tissue barriers and for use as microflameholders. In a preferred embodiment for …

US PATENT DOCUMENTS 6,030.827 A 2/2000 Davis et al. 6,032,059 A 2/2000 Henning et
al. 4,794.926. A* 1/1989 Munsch et al.............. 606/183 6,041,253 A 3/2000 Kost et al …

Microneedle devices and methods of manufacture are pro vided for transport of molecules or
energy across or into biological barriers, such as skin. The device can comprise one or more …

Microneedle devices for transport of therapeutic and diag nostic materials and/or energy
across tissue barriers, and methods for manufacturing the devices, are provided. The …

A microneedle array, constructed of silicon and silicon dioxide compounds or of a molded
plastic material, is provided to penetrate the stratum corneum and epidermis layers of skin …

A glucose sensor in the form of a skin patch 2 has a microneedle 4 which painlessly
penetrates the skin to draw out interstitial fluid. The interstitial fluid passes to a common …

Microneedle devices are provided for controlled sampling of biological fluids in a minimally-
invasive, painless, and con venient manner. The microneedle devices permit in vivo sensing …

Simple microneedle devices for delivery of drugs across or into biological tissue are
provided, which permit drug delivery at clinically relevant rates across or into skin or other …