The role of cell‐penetrating peptides in potential anti‐cancer therapy
M Zhou, X Zou, K Cheng, S Zhong, Y Su… - Clinical and …, 2022 - Wiley Online Library
Due to the complex physiological structure, microenvironment and multiple physiological
barriers, traditional anti‐cancer drugs are severely restricted from reaching the tumour site …
barriers, traditional anti‐cancer drugs are severely restricted from reaching the tumour site …
Angiopep-2-modified nanoparticles for brain-directed delivery of therapeutics: A review
S Habib, M Singh - Polymers, 2022 - mdpi.com
Nanotechnology has opened up a world of possibilities for the treatment of brain disorders.
Nanosystems can be designed to encapsulate, carry, and deliver a variety of therapeutic …
Nanosystems can be designed to encapsulate, carry, and deliver a variety of therapeutic …
Peptides as pharmacological carriers to the brain: promises, shortcomings and challenges
S Parrasia, I Szabò, M Zoratti… - Molecular …, 2022 - ACS Publications
Central nervous system (CNS) diseases are among the most difficult to treat, mainly
because the vast majority of the drugs fail to cross the blood-brain barrier (BBB) or to reach …
because the vast majority of the drugs fail to cross the blood-brain barrier (BBB) or to reach …
[HTML][HTML] Cell-penetrating peptides as part of therapeutics used in cancer research
M Matijass, I Neundorf - Medicine in Drug Discovery, 2021 - Elsevier
Peptides have gained more and more interest as therapeutics for different fields of medical
indications. Built up via a peptide bond from naturally occurring amino acids they stand out …
indications. Built up via a peptide bond from naturally occurring amino acids they stand out …
Interactions of Nanoscale Self-Assembled Peptide-Based Assemblies with Glioblastoma Cell Models and Spheroids
CG Lebedenko, ME Murray, BG Goncalves… - ACS …, 2023 - ACS Publications
Peptide nanoassemblies have garnered remarkable importance in the development of novel
nanoscale biomaterials for drug delivery into tumor cells. Taking advantage of receptor …
nanoscale biomaterials for drug delivery into tumor cells. Taking advantage of receptor …
DA7R: a 7-letter Zip code to target PDAC
S Parrasia, A Rossa, N Roncaglia, A Mattarei… - Pharmaceutics, 2023 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer,
and is among the most aggressive and still incurable cancers. Innovative and successful …
and is among the most aggressive and still incurable cancers. Innovative and successful …
Potassium and chloride ion channels in cancer: a novel paradigm for cancer therapeutics
Cancer is a collection of diseases caused by specific changes at the genomic level that
support cell proliferation indefinitely. Traditionally, ion channels are known to control a …
support cell proliferation indefinitely. Traditionally, ion channels are known to control a …
Entrepreneurial drug hunter: macrocyclic peptide modalities
T Sawyer - Contemporary Accounts in Drug Discovery and …, 2022 - Wiley Online Library
After nearly 50 years of research and development, peptide therapeutics have dramatically
evolved from rather simple chemical structures (oftentimes linear and relatively short …
evolved from rather simple chemical structures (oftentimes linear and relatively short …
Targeting Specific Barriers
Ü Langel - CPP, Cell-Penetrating Peptides, 2023 - Springer
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