Saliva in the diagnosis of diseases

CZ Zhang, XQ Cheng, JY Li, P Zhang, P Yi… - International journal of …, 2016 - nature.com
Saliva is secreted from the salivary glands and has multiple functions, including mouth
cleaning and protection, antibacterial effects and digestion. With the rapid advancement in …

Overview of oral potentially malignant disorders: from risk factors to specific therapies

L Lorini, C Bescós Atín, S Thavaraj, U Müller-Richter… - Cancers, 2021 - mdpi.com
Simple Summary Oral potentially malignant disorders (OPMDs) include a group of oral
mucosal diseases with different morphological characteristics that are able to progress to …

Evaluation of proinflammatory, NF-kappaB dependent cytokines: IL-1α, IL-6, IL-8, and TNF-α in tissue specimens and saliva of patients with oral squamous cell …

K Babiuch, B Kuśnierz-Cabala, B Kęsek… - Journal of Clinical …, 2020 - mdpi.com
Background: Oral squamous cell carcinoma (OSCC) is a life-threatening disease. It could be
preceded by oral potentially malignant disorders (OPMDs). It was confirmed that chronic …

Salivary cytokines as biomarkers for oral squamous cell carcinoma: a systematic review

E Ferrari, ME Pezzi, D Cassi, TA Pertinhez… - International journal of …, 2021 - mdpi.com
The prognosis of patients with oral squamous carcinoma (OSCC) largely depends on the
stage at diagnosis, the 5-year survival rate being approximately 30% for advanced tumors …

The inflammatory effects of TNF-α and complement component 3 on coagulation

MJ Page, J Bester, E Pretorius - Scientific reports, 2018 - nature.com
Tissue necrosis factor-α (TNF-α) and complement component 3 (C3) are two well-known pro-
inflammatory molecules. When TNF-α is upregulated, it contributes to changes in …

[HTML][HTML] Salivary tumour necrosis factor-α as a biomarker in oral leukoplakia and oral squamous cell carcinoma

G Deepthi, SRK Nandan… - Asian Pacific journal of …, 2019 - ncbi.nlm.nih.gov
Background: Oral cancer is one of the life threatening disease which requires an availability
of a biomarker for its early detection and also for effective treatment strategies. The current …

Salivary biomarkers in oral squamous cell carcinoma: a proteomic overview

G Riccardi, MG Bellizzi, I Fatuzzo, F Zoccali… - Proteomes, 2022 - mdpi.com
Background: Oral squamous cell carcinoma (OSCC) is one of the most frequent cancers
worldwide. Endoscopic methods may be useful in the evaluation of oral injuries even though …

Salivary cytokines as biomarkers of oral cancer: a systematic review and meta-analysis

MMA Chiamulera, CB Zancan, AP Remor, MF Cordeiro… - BMC cancer, 2021 - Springer
Background Oral cancer (OC) is usually diagnosed at advanced clinical stages due to its
asymptomatic nature and absence of pathognomonic signs in its early development phase …

Role of salivary MicroRNA and cytokines in the diagnosis and prognosis of oral squamous cell carcinoma

FJ Manzano-Moreno, VJ Costela-Ruiz… - International journal of …, 2021 - mdpi.com
Oral squamous cell carcinoma (OSCC) is the most prevalent oral malignant tumor
worldwide. An early diagnosis can have a major positive impact on its prognosis. Human …

Potential non-invasive biomarkers for early diagnosis of oral squamous cell carcinoma

V Dikova, E Jantus-Lewintre, J Bagan - Journal of Clinical Medicine, 2021 - mdpi.com
This study aimed to investigate the role of a panel of salivary cytokines as biomarkers for
early detection oral squamous cell carcinoma (OSCC), comparing their levels among …