A severe decline in child births has occurred over the past half century, which will lead to
considerable population declines, particularly in industrialized regions. A crucial question is …

Cancer stem cells (CSCs) show a self-renewal capacity and differentiation potential that
contribute to tumor progression and therapy resistance. However, the underlying processes …

It is predicted that Japan and European Union will soon experience appreciable decreases
in their populations due to persistently low total fertility rates (TFR) below replacement level …

Testicular germ cell tumours are at the crossroads of developmental and neoplastic
processes. Their cause has not been fully elucidated but differences in incidences suggest …

Induced pluripotent stem cells (iPSCs) are a type of pluripotent stem cells generated directly
from mature cells through the introduction of key transcription factors. iPSCs can be …

Testicular Cancer — Discoveries and Updates | NEJM Skip to main content NEJM Group
Follow Us Facebook Twitter Instagram YouTube LinkedIn Prepare to become a physician, build …

Endogenous small RNAs (miRNAs) regulate gene expression by mechanisms conserved
across metazoans. While the number of verified human miRNAs is still expanding, only few …

The germ-cell tumours are a fascinating group of neoplasms because of their unusual
biology and the spectacular therapeutic results that have been obtained in these tumours …

Cellular apoptosis appears to be a constant feature in the adult testis and during early
development. This is essential because mammalian spermatogenesis is a complex process …

TWEAK is a multifunctional cytokine that controls many cellular activities including
proliferation, migration, differentiation, apoptosis, angiogenesis and inflammation. TWEAK …