Tumor neoantigen is the truly foreign protein and entirely absent from normal human
organs/tissues. It could be specifically recognized by neoantigen-specific T cell receptors …

Immunotherapy has moved to the center stage of cancer treatment with the recent success of
trials in solid tumors with PD-1/PD-L1 axis blockade. Programmed death-1 or PD-1 is a …

We undertook a comprehensive proteogenomic characterization of 95 prospectively
collected endometrial carcinomas, comprising 83 endometrioid and 12 serous tumors. This …

Tobacco smoking increases the risk of at least 17 classes of human cancer. We analyzed
somatic mutations and DNA methylation in 5243 cancers of types for which tobacco smoking …

Sequencing complete tumor genomes and exomes has sparked the cancer field's interest in
mutation signatures for identifying the tumor's carcinogen. This review and meta‐analysis …

The present review aimed to outline different types of RNAs in cancer diagnostics and
treatment, and to provide novel insights into their clinical applications. RNAs, including …

Background E-cigarettes are currently being debated regarding their possible role in
smoking cessation and as they are becoming increasingly popular, the research to date …

That each of us is truly biologically unique, extending to even monozygotic," identical" twins,
is not fully appreciated. Now that it is possible to perform a comprehensive" omic" …

Abstract Treatment strategies for patients with advanced solid tumors have traditionally been
based on three different paradigms: surgery, cytotoxics (chemotherapy or radiation therapy) …

Relapse of acute lymphoblastic leukemia (ALL) remains a leading cause of childhood
cancer-related death. Prior studies have shown clonal mutations at relapse often arise from …