mRNA has broad potential as a therapeutic. Current clinical efforts are focused on
vaccination, protein replacement therapies, and treatment of genetic diseases. The clinical …

Biomedicine represents one of the main study areas for dendrimers, which have proven to
be valuable both in diagnostics and therapy, due to their capacity for improving solubility …

The host immune system is highly compromised in case of viral infections and relapses are
very common. The capacity of the virus to destroy the host cell by liberating its own DNA or …

Since the first dendrimer was reported in 1978 by Fritz Vögtle, dendrimer research has
grown exponentially, from synthesis to application in the past four decades. The distinct …

The facile preparation, modular design, and multiresponsiveness are extremely critical for
developing pervasive nanoplatforms to meet heterogeneous applications. Here, cationic …

Gene vectors are nucleic acids that carry genetic materials or gene editing devices into cells
to exert the sustained production of therapeutic proteins or to correct erroneous genes of the …

Dendritic polymers have highly branched threedimensional architectures, the fourth type
apart from linear, crosslinked, and branched one. They possess not only a large number of …

Messenger RNA (mRNA)based therapies offer great promise for the treatment of a variety
of diseases. In 2020, two FDA approvals of mRNAbased vaccines have elevated mRNA …

Surface charge of biological and medical nanocarriers has been demonstrated to play an
important role in cellular uptake. Owing to the unique physicochemical properties, charge …

Self-assembly is the process of association of individual units of a material into highly
arranged/ordered structures/patterns. It imparts unique properties to both inorganic and …