Evolution of approaches to increase the salt tolerance of crops

M Ashraf, R Munns - Critical Reviews in Plant Sciences, 2022 - Taylor & Francis
The existence of salinity stress can be traced well before the domestication of crops, but the
documentation and mitigation of this menace started only 100 years ago. Due to the …

[HTML][HTML] Structure and pharmacology of pentameric receptor channels: from bacteria to brain

PJ Corringer, F Poitevin, MS Prevost, L Sauguet… - Structure, 2012 - cell.com
Orthologs of the pentameric receptor channels that mediate fast synaptic transmission in the
central and peripheral nervous systems have been found in several bacterial species and in …

Cryo-EM structure of a fungal mitochondrial calcium uniporter

NX Nguyen, JP Armache, C Lee, Y Yang, W Zeng… - Nature, 2018 - nature.com
The mitochondrial calcium uniporter (MCU) is a highly selective calcium channel localized to
the inner mitochondrial membrane. Here, we describe the structure of an MCU orthologue …

Therapeutics—how to treat phase separation-associated diseases

RJ Wheeler - Emerging Topics in Life Sciences, 2020 - portlandpress.com
Liquid–liquid phase separation has drawn attention as many neurodegeneration or cancer-
associated proteins are able to form liquid membraneless compartments (condensates) by …

[HTML][HTML] Utilization of genes encoding osmoprotectants in transgenic plants for enhanced abiotic stress tolerance

MS Khan, D Ahmad, MA Khan - Electronic Journal of Biotechnology, 2015 - Elsevier
Global agriculture in the context of growing and expanding populations is under huge
pressure to provide increased food, feed, and fiber. The recent phenomenon of climate …

[HTML][HTML] Precise prediction of phase-separation key residues by machine learning

J Sun, J Qu, C Zhao, X Zhang, X Liu, J Wang… - Nature …, 2024 - nature.com
Understanding intracellular phase separation is crucial for deciphering transcriptional
control, cell fate transitions, and disease mechanisms. However, the key residues, which …

Enhancing tilapia fish myosin solubility using proline in low ionic strength solution

Y Zhou, H Yang - Food Chemistry, 2020 - Elsevier
The effects of using proline to solubilise fish myosin under low ionic strength conditions were
studied. After solubilising myosin in 0.1 M NaCl containing 5, 10, 15, and 20 mM proline …

[HTML][HTML] Conformational rigidity and protein dynamics at distinct timescales regulate PTP1B activity and allostery

MS Choy, Y Li, LESF Machado, MBA Kunze… - Molecular cell, 2017 - cell.com
Protein function originates from a cooperation of structural rigidity, dynamics at different
timescales, and allostery. However, how these three pillars of protein function are integrated …

[HTML][HTML] Comparative bio-accumulation of osmoprotectants in saline stress tolerating plants: A review

D Mehta, S Vyas - Plant Stress, 2023 - Elsevier
Osmoprotectants are a diverse group of low molecular weight organic solutes that can help
in balancing the osmotic potential in plants surviving under salinity stress. These …

TRIM 21: a cytosolic Fc receptor with broad antibody isotype specificity

S Foss, R Watkinson, I Sandlie, LC James… - Immunological …, 2015 - Wiley Online Library
Antibodies are key molecules in the fight against infections. Although previously thought to
mediate protection solely in the extracellular environment, recent research has revealed that …