Temperature and pressure denaturation of chignolin: Folding and unfolding simulation by multibaric‐multithermal molecular dynamics method

H Okumura - Proteins: Structure, Function, and Bioinformatics, 2012 - Wiley Online Library
A multibaric‐multithermal molecular dynamics (MD) simulation of a 10‐residue protein,
chignolin, was performed. All‐atom model with the Amber parm99SB force field was used for …

Water‐mediated interactions destabilize proteins

T Sumi, H Imamura - Protein Science, 2021 - Wiley Online Library
Proteins are folded to avoid exposure of the nonpolar groups to water because water‐
mediated interactions between nonpolar groups are a promising factor in the …

Interplay between lipid interaction and homo-coiling of membrane-tethered coiled-coil peptides

M Rabe, HR Zope, A Kros - Langmuir, 2015 - ACS Publications
The designed coiled-coil-forming peptides E [(EIAALEK) 3] and K [(KIAALKE) 3] are known
to trigger efficient membrane fusion when they are tethered to lipid vesicles in the form of …

Probing conformational and functional substates of calmodulin by high pressure FTIR spectroscopy: influence of Ca 2+ binding and the hypervariable region of K …

N Erwin, S Patra, R Winter - Physical Chemistry Chemical Physics, 2016 - pubs.rsc.org
The ubiquitous Ca2+-sensing protein calmodulin (CaM) interacts with more than 300
diverse target proteins that are involved in numerous signaling pathways in eukaryotic cells …

An FT-IR Study on Packing Defects in Mixed β-Aggregates of Poly(l-glutamic acid) and Poly(d-glutamic acid): A High-Pressure Rescue from a Kinetic Trap

Y Yamaoki, H Imamura, A Fulara, S Wójcik… - The Journal of …, 2012 - ACS Publications
Under favorable conditions of pH and temperature, poly (l-glutamic acid)(PLGA) adopts
different types of secondary and quaternary structures, which include spiral assemblies of …

NMR and computation reveal a pressure-sensitive folded conformation of trp-cage

S Kitazawa, MJ Fossat, SA McCallum… - The Journal of …, 2017 - ACS Publications
Beyond defining the structure and stability of folded states of proteins, primary amino acid
sequences determine all of the features of their conformational landscapes. Characterizing …

Differences in the structural stability and cooperativity between monomeric variants of natural and de novo Cro proteins revealed by high-pressure Fourier transform …

H Imamura, Y Isogai, M Kato - Biochemistry, 2012 - ACS Publications
It is widely accepted that pressure affects the structure and dynamics of proteins; however,
the underlying mechanism remains unresolved. Our previous studies have investigated the …

压力诱导溶液中蛋白质构象变化的谱学研究

张敏, 吴玉清 - 化学进展, 2011 - manu56.magtech.com.cn
摇孕则藻泽泽怎则藻澡葬泽遭藻藻灶怎泽藻凿枣燥则蚤灶增藻泽贼蚤早葬贼蚤灶早贼澡藻怎灶
枣燥造凿蚤灶早燥枣责则燥贼藻蚤灶泽葬灶凿枣燥则则藻增藻葬造蚤灶早贼澡藻蚤则枣燥造凿 …

[PDF][PDF] Modelos simples para estudiar el efecto de la presión en el plegamiento de proteínas

R Perezzan Rodríguez - 2015 - docta.ucm.es
2 Introducción penderán de magnitudes físicas que pueden afectar en su reactividad, como
por ejemplo la temperatura. el pH o la presión. El poder conocer cómo cualquiera de estas …

Preserving Proteins Under High Pressure and Low Temperature

T Takekiyo, M Kato, Y Yoshimura - Protein Structure, 2012 - books.google.com
A promising method of preserving aqueous protein solutions is to subject them to high
pressure and low temperature. However, two significant issues can arise under these …