Oral cancer, as one of the most prevalent and invasive cancers that invade local tissue, can
cause metastasis, and have high mortality. In 2018, around 355,000 worldwide oral cancers …

With the rapid development of biomedicine, people have a deeper understanding with the
biological characteristics of malignant tumors, and begin to notice that in most tumors, there …

Background The development of drug resistance in oral squamous cell carcinoma (OSCC)
that frequently leads to recurrence and metastasis after initial treatment remains an …

Hypoxia is an important pathological hallmark of the tumor microenvironment, associated
with metabolic alterations, cell proliferation, aggressiveness, metastasis, and therapy …

Oral cavity and oropharyngeal carcinomas (oral cancer) represents a significant cause of
morbidity and mortality. Despite efforts in improving early diagnosis and treatment, the 5 …

CD44 is widely expressed on the surface of most tissues and all hematopoietic cells, and
regulates many genes associated with cell adhesion, migration, proliferation, differentiation …

Cancer immunomodulation has been implicated in the development of oral squamous cell
carcinoma (OSCC), however the role of specific immunomodulatory proteins is not …

Traditional therapeutics have encountered a bottleneck caused by diagnosis delay and
subjective and unreliable assessment. Biomarkers can overcome this bottleneck and guide …

Background Oral squamous cell carcinoma (OSCC) is an oral and maxillofacial malignancy
with a high incidence worldwide. Accumulating evidence indicates that circular RNAs …

Background/purpose Palbociclib is an FDA-approved cyclin-dependent kinase (CDK) 4/6
inhibitor that has been clinically proven to be effective in breast cancer. However, its use in …