Molecular mechanism of curcumin action in signaling pathways: Review of the latest research

P Liczbiński, J Michałowicz… - Phytotherapy …, 2020 - Wiley Online Library
Recently, many studies have been conducted trying to explain the molecular mechanism of
curcumin action in various pathological states of the cell and the organism. Curcumin is …

[HTML][HTML] Oxidative stress-induced apoptosis and autophagy: Balancing the contrary forces in spermatogenesis

P Sharma, N Kaushal, LR Saleth, S Ghavami… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Spermatogenesis is a complex process in the testis and is a cornerstone of male infertility.
The abundance of unsaturated fatty acid and high cell division rate make male germs cells …

Potential of curcumin and niacin-loaded targeted chitosan coated liposomes to activate autophagy in hepatocellular carcinoma cells: An in vitro evaluation in HePG2 …

NAN Hanafy, RF Sheashaa, EA Moussa… - International journal of …, 2023 - Elsevier
The objective of this study is to activate autophagy in hepatocellular carcinoma for the
enhancement of its cellular degradation. Liposomes incorporated chitosan in the core used …

The role of curcumin/curcuminoids during gastric cancer chemotherapy: a systematic review of non-clinical study

M Najafi, K Mortezaee, M Rahimifard, B Farhood… - Life sciences, 2020 - Elsevier
Aims Chemotherapy is an effective therapeutic modality which is commonly used for battling
various cancers. However, several side effects induced by chemotherapeutic drugs would …

[HTML][HTML] Promising role of curcumin against viral diseases emphasizing COVID-19 management: A review on the mechanistic insights with reference to host-pathogen …

S Dhar, P Bhattacharjee - Journal of Functional Foods, 2021 - Elsevier
Curcumin has already acknowledged immense interest from both medical and scientific
research because of its multifaceted activity. To date, the promising effects of curcumin were …

Macrophage targeted polymeric curcumin nanoparticles limit intracellular survival of Mycobacterium tuberculosis through induction of autophagy and augment anti …

PK Gupta, P Jahagirdar, D Tripathi… - Frontiers in …, 2023 - frontiersin.org
Rapid emergence of antibiotic resistance in tuberculosis has left us with limited resources to
treat and manage multi drug resistant (MDR) cases of tuberculosis, prompting the …

Curcumin induces autophagic cell death in human thyroid cancer cells

L Zhang, S Xu, X Cheng, J Wu, L Wu, Y Wang, X Wang… - Toxicology in Vitro, 2022 - Elsevier
Curcumin, a polyphenolic compound, is a well-known anticancer agent, although its poor
bioavailability remains a big concern. Recent studies suggest that autophagy-targeted …

ROS-generating, pH-responsive and highly tunable reduced graphene oxide-embedded microbeads showing intrinsic anticancer properties and multi-drug co …

A Boddu, OS Reddy, D Zhang, KSVK Rao, WF Lai - Drug Delivery, 2022 - Taylor & Francis
The development of effective carriers enabling combination cancer therapy is of practical
importance due to its potential to enhance the effectiveness of cancer treatment. However …

Reconnoitering the therapeutic role of curcumin in disease prevention and treatment: Lessons learnt and future directions

BM Sivani, M Azzeh, R Patnaik, A Pantea Stoian… - Metabolites, 2022 - mdpi.com
Turmeric is a plant with a very long history of medicinal use across different cultures.
Curcumin is the active part of turmeric, which has exhibited various beneficial physiological …

Impact of curcumin on replicative and chronological aging in the Saccharomyces cerevisiae yeast

K Stępień, D Wojdyła, K Nowak, M Mołoń - Biogerontology, 2020 - Springer
Curcumin is a biologically active compound of vegetable origin which has a hormetic effect.
Pro-health and anti-aging properties of curcumin have been known for years. The main …