Unraveling Dengue Virus Diversity in Asia: An Epidemiological Study through Genetic Sequences and Phylogenetic Analysis

J Phadungsombat, EE Nakayama, T Shioda - Viruses, 2024 - mdpi.com
Dengue virus (DENV) is the causative agent of dengue. Although most infected individuals
are asymptomatic or present with only mild symptoms, severe manifestations could …

Multi-omics in exploring the pathophysiology of diabetic retinopathy

X Li, XJ Dong, W Zhang, Z Shi, Z Liu, Y Sa… - Frontiers in Cell and …, 2024 - frontiersin.org
Diabetic retinopathy (DR) is a leading global cause of vision impairment, with its prevalence
increasing alongside the rising rates of diabetes mellitus (DM). Despite the retina's complex …

Increased frequencies of highly activated regulatory T cells skewed to a T helper 1-like phenotype with reduced suppressive capacity in dengue patients

S Sann, B Heng, HTM Vo, R Arroyo Hornero, S Lay… - Mbio, 2024 - Am Soc Microbiol
The pathogenesis of dengue involves a complex interplay between the viral factor and the
host immune response. A mismatch between the infecting serotype and the adaptive …

[HTML][HTML] Systems immunology of transcriptional responses to viral infection identifies conserved antiviral pathways across macaques and humans

K Ratnasiri, H Zheng, J Toh, Z Yao, V Duran, M Donato… - Cell Reports, 2024 - cell.com
Viral pandemics and epidemics pose a significant global threat. While macaque models of
viral disease are routinely used, it remains unclear how conserved antiviral responses are …

First clinical reports of acute hantavirus and dengue infections among pregnant women in the Caribbean

KO Douglas, M Gittens-St. Hilaire - Infectious Diseases, 2024 - Taylor & Francis
Background Hantavirus and dengue virus infections lead to diseases causing economic and
public health concerns. Acute hantavirus infections can lead to similar clinical haemorrhagic …

B cell receptor dependent enhancement of dengue virus infection

C Gebo, CSC Hardy, BD McElvany, NR Graham… - PLoS …, 2024 - journals.plos.org
Dengue virus (DENV) is the causative agent of dengue, a mosquito-borne disease that
represents a significant and growing public health burden around the world. A unique …

Dengue NS1 interaction with lipids alters its pathogenic effects on monocyte derived macrophages

S Dayarathna, B Senadheera, C Jeewandara… - Journal of Biomedical …, 2024 - Springer
Background While dengue NS1 antigen has been shown to be associated with disease
pathogenesis in some studies, it has not been linked in other studies, with the reasons …

[HTML][HTML] Myeloid-Derived Suppressor Cells Induce Exhaustion-Like CD8+ T Cells during JEV Infection

W Zhang, Q Yu, X Gao, H Chen, J Su… - International …, 2024 - pmc.ncbi.nlm.nih.gov
Japanese encephalitis (JE), caused by Japanese encephalitis virus (JEV), is a mosquito-
borne zoonotic disease and a leading cause of viral encephalitis worldwide. While JEV has …

Building a single cell transcriptome-based coordinate system for cell ID with SURE

F Zeng, J Han - bioRxiv, 2024 - biorxiv.org
The surge in single-cell transcriptome data necessitates a unified cell identification system.
We propose a strategy that uses metacells as landmarks, coupled with a data-driven method …

Immune responses and severe dengue: what have we learned?

GN Malavige, GS Ogg - Current Opinion in Infectious Diseases, 2024 - journals.lww.com
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