[HTML][HTML] Neuropathic pain: from mechanisms to treatment

NB Finnerup, R Kuner, TS Jensen - Physiological reviews, 2020 - journals.physiology.org
Neuropathic pain caused by a lesion or disease of the somatosensory nervous system is a
common chronic pain condition with major impact on quality of life. Examples include …

Advances in diagnosis, classification, pathophysiology, and management of trigeminal neuralgia

L Bendtsen, JM Zakrzewska, TB Heinskou… - The Lancet …, 2020 - thelancet.com
Trigeminal neuralgia is a very painful neurological condition with severe, stimulus-evoked,
short-lasting stabbing pain attacks in the face. The past decade has offered new insights into …

Identification of the NRF2 transcriptional network as a therapeutic target for trigeminal neuropathic pain

C Vasavda, R Xu, J Liew, R Kothari, RS Dhindsa… - Science …, 2022 - science.org
Trigeminal neuralgia, historically dubbed the “suicide disease,” is an exceedingly painful
neurologic condition characterized by sudden episodes of intense facial pain. Unfortunately …

Incidence of trigeminal neuralgia: A population‐based study in Central Sweden

T Svedung Wettervik, D Snel… - … Journal of Pain, 2023 - Wiley Online Library
Background The primary aim of this observational study was to determine the incidence of
trigeminal neuralgia (TN) in a county in central Sweden. The secondary aim was to …

The pathophysiology of trigeminal neuralgia: a molecular review

B Dong, R Xu, M Lim - Journal of neurosurgery, 2023 - thejns.org
OBJECTIVE The goal of this study was to provide a comprehensive overview of the current
understanding of molecular and genetic mechanisms underlying the pathophysiology of …

The underlying pathogenesis of neurovascular compression syndromes: a systematic review

B Szmyd, J Sołek, M Błaszczyk, J Jankowski… - Frontiers in Molecular …, 2022 - frontiersin.org
Neurovascular compression syndromes (NVC) are challenging disorders resulting from the
compression of cranial nerves at the root entry/exit zone. Clinically, we can distinguish the …

Mesenchymal stem/stromal cells and their extracellular vesicle progeny decrease injury in poststenotic swine kidney through different mechanisms

Y Zhao, X Zhu, L Zhang, CM Ferguson… - Stem cells and …, 2020 - liebertpub.com
Novel therapies are needed to address the increasing prevalence of chronic kidney disease.
Mesenchymal stem/stromal cells (MSCs) and MSC-derived extracellular vesicles (EVs) …

Sex differences in trigeminal neuralgia: a focus on radiological and clinical characteristics

G De Stefano, D Litewczuk, C Mollica, G Di Pietro… - Neurological …, 2023 - Springer
Background It is well established that trigeminal neuralgia is more prevalent in females than
in males. Neurovascular compression with morphological changes of the trigeminal root …

Narrow ovale foramina may be involved in the development of primary trigeminal neuralgia

S Li, C Liao, M Qian, X Yang, W Zhang - Frontiers in Neurology, 2022 - frontiersin.org
Background The etiology of primary trigeminal neuralgia remains unclear and is worthy of
further study; In this study, the morphometric characteristics of ovale foramina between …

A review of the clinical and therapeutic implications of neuropathic pain

E Balzani, A Fanelli, V Malafoglia, M Tenti, S Ilari… - Biomedicines, 2021 - mdpi.com
Understanding neuropathic pain presents several challenges, given the various
mechanisms underlying its pathophysiological classification and the lack of suitable tools to …