Aristolochic acids (AAs) are a group of naturally occurring compounds present in many plant
species of the Aristolochiaceae family. Exposure to AA is a significant risk factor for severe …

An epidemic of chronic kidney disease of unknown origin has emerged in the last decade in
Central America and has been named Mesoamerican nephropathy. This form of chronic …

Aristolochic acid, a potent human carcinogen produced by Aristolochia plants, is associated
with urothelial carcinoma of the upper urinary tract (UUC). Following metabolic activation …

The term “aristolochic acid nephropathy”(AAN) is used to include any form of toxic interstitial
nephropathy that is caused either by ingestion of plants containing aristolochic acids (AA) as …

Endemic (Balkan) nephropathy (EN), a devastating renal disease affecting men and women
living in rural areas of Bosnia, Bulgaria, Croatia, Romania, and Serbia, is characterized by …

Aristolochic acids (AAs) are a group of toxins commonly present in the plants of genus
Aristolochia and Asarum, which are spread all over the world. Since the 1990s, AA-induced …

In humans, exposure to aristolochic acid (AA) is associated with urothelial carcinoma of the
upper urinary tract (UTUC). Exome sequencing of UTUCs from 19 individuals with …

AIMS OF THE STUDY: More than 100 cases of nephropathy over the last 10 years caused
by the systemic and longer term application of Chinese snakeroot (Aristolochia fangchi) …

Endemic (Balkan) nephropathy is a chronic tubulointerstitial disease frequently
accompanied by urothelial cell carcinomas of the upper urinary tract. This disorder has …

Nitro group containing xenobiotics include drugs, cancer chemotherapeutic agents,
carcinogens (eg, nitroarenes and aristolochic acid) and explosives. The nitro group …