Understanding laterality disorders and the left-right organizer: Insights from zebrafish

K Forrest, AC Barricella, SA Pohar… - Frontiers in Cell and …, 2022 - frontiersin.org
Vital internal organs display a left-right (LR) asymmetric arrangement that is established
during embryonic development. Disruption of this LR asymmetry—or laterality—can result in …

ZebRA: An overview of retinoic acid signaling during zebrafish development

E Samarut, D Fraher, V Laudet, Y Gibert - Biochimica et Biophysica Acta …, 2015 - Elsevier
Highlights•We reviewed the biology of RA signaling in the zebrafish model.•We reviewed the
latest advances in RA signaling in patterning and left right asymmetry.•We reviewed the …

Kupffer's vesicle size threshold for robust left–right patterning of the zebrafish embryo

JJ Gokey, Y Ji, HG Tay, B Litts… - Developmental …, 2016 - Wiley Online Library
Background: Motile cilia in the “organ of asymmetry” create directional fluid flows that are
vital for left–right (LR) asymmetric patterning of vertebrate embryos. Organ function often …

Cullin 3 exon 9 deletion in familial hyperkalemic hypertension impairs Cullin3-ring-E3 ligase (CRL3) dynamic regulation and cycling

I Kouranti, W Abdel Khalek, S Mazurkiewicz… - International Journal of …, 2022 - mdpi.com
Cullin 3 (CUL3) is the scaffold of Cullin3 Ring E3-ligases (CRL3s), which use various BTB-
adaptor proteins to ubiquitinate numerous substrates targeting their proteasomal …

Asymmetry in dentition and shape of pharyngeal arches in the clonal fish Chrosomus eos-neogaeus: Phenotypic plasticity and developmental instability

C Leung, KK Duclos, T Grünbaum, R Cloutier… - PLoS …, 2017 - journals.plos.org
The effect of the environment may result in different developmental outcomes. Extrinsic
signals can modify developmental pathways and result in alternative phenotypes …

Generating diversity and specificity through developmental cell signaling

RV Hoch, P Soriano - Principles of Developmental Genetics, 2015 - Elsevier
Highly conserved cell-cell signaling pathways are used reiteratively during development to
instruct cellular proliferation, survival, migration, patterning, and differentiation. Responses …

Saltatory evolution of the ectodermal neural cortex gene family at the vertebrate origin

N Feiner, Y Murakami, L Breithut… - Genome biology and …, 2013 - academic.oup.com
The ectodermal neural cortex (ENC) gene family, whose members are implicated in
neurogenesis, is part of the kelch repeat superfamily. To date, ENC genes have been …