Exploring treatment options in cancer: tumor treatment strategies

B Liu, H Zhou, L Tan, KTH Siu, XY Guan - Signal transduction and …, 2024 - nature.com
Traditional therapeutic approaches such as chemotherapy and radiation therapy have
burdened cancer patients with onerous physical and psychological challenges …

Immunosurveillance in clinical cancer management

G Kroemer, TA Chan, AMM Eggermont… - CA: A Cancer Journal …, 2024 - Wiley Online Library
The progression of cancer involves a critical step in which malignant cells escape from
control by the immune system. Antineoplastic agents are particularly efficient when they …

Peptide-based agents for cancer treatment: current applications and future directions

NTT Nhàn, T Yamada, KH Yamada - International Journal of Molecular …, 2023 - mdpi.com
Peptide-based strategies have received an enormous amount of attention because of their
specificity and applicability. Their specificity and tumor-targeting ability are applied to …

Cranioencephalic functional lymphoid units in glioblastoma

C Dobersalske, L Rauschenbach, Y Hua, C Berliner… - Nature medicine, 2024 - nature.com
The ecosystem of brain tumors is considered immunosuppressed, but our current
knowledge may be incomplete. Here we analyzed clinical cell and tissue specimens derived …

Potential targeting of the tumor microenvironment to improve cancer virotherapy

ZX Liao, SH Hsu, SC Tang, I Kempson, PC Yang… - Pharmacology & …, 2023 - Elsevier
In 2015, oncolytic virotherapy was approved for clinical use, and in 2017, recombinant
adeno-associated virus (AAV) delivery was also approved. However, systemic …

Oncolytic virotherapy in cancer treatment: challenges and optimization prospects

L Chen, M Zuo, Q Zhou, Y Wang - Frontiers in Immunology, 2023 - frontiersin.org
Oncolytic viruses (OVs) are emerging cancer therapeutics that offer a multifaceted
therapeutic platform for the benefits of replicating and lysing tumor cells, being engineered …

Immunotherapy for glioblastoma: current state, challenges, and future perspectives

Y Liu, F Zhou, H Ali, JD Lathia, P Chen - Cellular & Molecular …, 2024 - nature.com
Glioblastoma (GBM) is an aggressive and lethal type of brain tumor in human adults. The
standard of care offers minimal clinical benefit, and most GBM patients experience tumor …

Glioblastoma therapy: past, present and future

E Obrador, P Moreno-Murciano… - International journal of …, 2024 - mdpi.com
Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer.
Although great efforts have been made by clinicians and researchers, no significant …

Glioblastoma vaccines: past, present, and opportunities

Z Xiong, I Raphael, M Olin, H Okada, X Li… - …, 2024 - thelancet.com
Glioblastoma (GBM) is one of the most lethal central nervous systems (CNS) tumours in
adults. As supplements to standard of care (SOC), various immunotherapies improve the …

'Slicing'glioblastoma drivers with the Swiss cheese model

OYT Pumar, JD Lathia, DC Watson, D Bayik - Trends in cancer, 2024 - cell.com
The Swiss cheese model is used to assess risks and explain accidents in a variety of
industries. This model can be applied to dissect the homeostatic mechanisms whose …