The pathophysiology of hyperglycemia in older adults: clinical considerations

PG Lee, JB Halter - Diabetes care, 2017 - Am Diabetes Assoc
Nearly a quarter of older adults in the US have type 2 diabetes, and this population is
continuing to increase with the aging of the population. Older adults are at high risk for the …

Understanding and overcoming metformin gastrointestinal intolerance

F Bonnet, A Scheen - Diabetes, Obesity and Metabolism, 2017 - Wiley Online Library
Metformin is the most widely prescribed drug for patients with type 2 diabetes mellitus and
the first‐line pharmacological option as supported by multiple international guidelines, yet a …

Pharmacological management of obesity: an endocrine Society clinical practice guideline

CM Apovian, LJ Aronne, DH Bessesen… - The Journal of …, 2015 - academic.oup.com
Objective: To formulate clinical practice guidelines for the pharmacological management of
obesity. Participants: An Endocrine Society-appointed Task Force of experts, a …

[PDF][PDF] Сахарный диабет 2 типа

АС Аметов - Проблемы и решения, 2014 - e-library.sammu.uz
Аннотация Современная диабетология обращает самое серьезное внимание на
метаболизм жировой ткани потому, что жировая ткань очень тесно связана с …

Review on rosmarinic acid extraction, fractionation and its anti-diabetic potential

YL Ngo, CH Lau, LS Chua - Food and Chemical Toxicology, 2018 - Elsevier
Rosmarinic acid is a bioactive phytochemical that can be found in many herbs as
ethnomedicines. It possesses remarkable pharmacological activities, and thus leading to its …

Sodium-glucose cotransporter-2 inhibitors: Understanding the mechanisms for therapeutic promise and persisting risks

RJ Perry, GI Shulman - Journal of Biological Chemistry, 2020 - ASBMB
In a healthy person, the kidney filters nearly 200 g of glucose per day, almost all of which is
reabsorbed. The primary transporter responsible for renal glucose reabsorption is sodium …

DPP4 in cardiometabolic disease: recent insights from the laboratory and clinical trials of DPP4 inhibition

J Zhong, A Maiseyeu, SN Davis… - Circulation …, 2015 - Am Heart Assoc
The discovery of incretin-based medications represents a major therapeutic advance in the
pharmacological management of type 2 diabetes mellitus (T2DM), as these agents avoid …

Bioactive compounds from culinary herbs inhibit a molecular target for type 2 diabetes management, dipeptidyl peptidase IV

AM Bower, LM Real Hernandez… - Journal of agricultural …, 2014 - ACS Publications
Greek oregano (Origanum vulgare), marjoram (Origanum majorana), rosemary (Rosmarinus
officinalis), and Mexican oregano (Lippia graveolens) are concentrated sources of bioactive …

Clinical Practice Guideline on management of patients with diabetes and chronic kidney disease stage 3b or higher (eGFR< 45 mL/min)

Guideline Development Group, H Bilo… - Nephrology Dialysis …, 2015 - academic.oup.com
Diabetes mellitus is becoming increasingly prevalent and is considered a rapidly growing
concern for healthcare systems. Besides the cardiovascular complications, diabetes mellitus …

Clinical considerations for use of initial combination therapy in type 2 diabetes

A Cahn, WT Cefalu - Diabetes Care, 2016 - Am Diabetes Assoc
Type 2 diabetes is a progressive disorder characterized by increasing hyperglycemia and
the need to gradually intensify therapy in order to achieve and maintain glycemic control …