Importance Tranexamic acid (TXA) is an efficient antifibrinolytic agent; however, concerns
remain about the potential adverse effects, particularly vascular occlusive events, that may …

BACKGROUND Tranexamic acid (TXA) is an inexpensive therapy effective at minimizing
perioperative blood loss and transfusion. However, it remains underutilized due to safety …

Results Four studies were included with a total of 436 patients. Three of the four studies had
small sample sizes. There was a low risk of attrition bias and reporting bias. Unclear risk of …

Background Tranexamic acid is a synthetic lysine-analogue antifibrinolytic that competitively
inhibits the activation of plasminogen to plasmin, it is a well-documented blood sparing …

Abstract Background and Objectives Major bleeding and receiving blood products in cancer
surgery are associated with increased postoperative complications and worse outcomes …

Introduction Reducing bleeding episodes is very important in haematology disorders like
von Willebrand disease (VWD) and Glanzmann thrombasthenia (GT). Replacement factors …

Background: Head and neck cancer (HNC) surgery is associated with high intraoperative
blood loss which may require urgent blood transfusion. Many strategies have been …

Results: There was no significant difference in intraoperative blood loss in all the three
groups. Both the tranexamic acid groups showed reduction in postoperative blood collection …

Pelvic vasculature is complex and inconsistent while pelvic bones impede access to pelvic
organs. These anatomical characteristics render pelvic surgery inherently difficult, and some …

Background: The prevalence of anemia in India is so high that majority of women presenting
for hysterectomy are already with borderline hemoglobin status and the perioperative blood …