Abstract NLRP3 (NOD-, LRR-and pyrin domain-containing protein 3) is an intracellular
sensor that detects a broad range of microbial motifs, endogenous danger signals and …

Recent studies have revealed novel forms of cell death beyond the canonical types of
cellular apoptosis and necrosis, and these novel forms of cell death are induced by extreme …

For topical treatment of skin cancer, the design of pH-responsive nanocarriers able to
selectively release the drug in the tumor acidic microenvironment represents a reliable …

Gout is a disease with acute and/or chronic inflammation and tissue damage induced by the
precipitation of monosodium urate crystal (MSU) crystals in bone joints, kidneys, and …

Malignant melanoma (MM) is the most lethal skin cancer. Despite a 4% reduction in mortality
over the past few years, an increasing number of new diagnosed cases appear each year …

Cutaneous melanoma is one of the most aggressive human cancers and is the deadliest
form of skin cancer, essentially due to metastases. Novel therapies are always required …

Sepsis is the host immune imbalance following infection and leads to organ dysfunction,
with highly complicated pathophysiology. To date, sepsis still lacks effective therapies with …

Sepsis is an uncontrolled host response to infection, resulting in a clinical syndrome
involving multiple organ dysfunctions. Cardiac damage is the most common organ damage …

Sažetak Surpassing heart diseases, cancer is taking the lead as the deadliest disease
because of its fast rate of spreading in all parts of the world. Tireless commitment to …

The malignant transformation of melanocytes causes several thousand deaths each year,
making melanoma an important public health concern. Melanoma is the most aggressive …