Pre-clinical models in implant dentistry: past, present, future

N Blanc-Sylvestre, P Bouchard, C Chaussain, C Bardet - Biomedicines, 2021 - mdpi.com
Biomedical research seeks to generate experimental results for translation to clinical
settings. In order to improve the transition from bench to bedside, researchers must draw …

Targeted drug delivery from titanium implants: a review of challenges and approaches

A Barik, N Chakravorty - Trends in Biomedical Research, 2020 - Springer
Titanium implants are considered the gold standard of treatment for dental and orthopedic
applications. Biocompatibility, low elasticity, and corrosion resistance are some of the key …

[HTML][HTML] Alveolar bone healing in rats: micro-CT, immunohistochemical and molecular analysis

JS Hassumi, G Mulinari-Santos, ALS Fabris… - Journal of Applied Oral …, 2018 - SciELO Brasil
Alveolar bone healing after upper incisor extraction in rats is a classical model of preclinical
studies. The underlying morphometric, cellular and molecular mechanism, however …

Plasma Electrolytic Oxidation as a Feasible Surface Treatment for Biomedical Applications: an in vivo study

TOB Polo, WPP Silva, GAC Momesso, TJ Lima-Neto… - Scientific reports, 2020 - nature.com
Objectives: In this in vivo animal study, we evaluated the effect of plasma electrolytic
oxidation (PEO) coating on the topographic and biological parameters of implants installed …

Osseointegration in osteoporotic‐like condition: A systematic review of preclinical studies

X Dereka, E Calciolari, N Donos… - Journal of periodontal …, 2018 - Wiley Online Library
Osteoporosis is one of the most common skeletal disorders affecting a significant
percentage of people worldwide. Research data suggested that systemic diseases such as …

Synergic action of systemic risedronate and local rutherpy in peri-implantar repair of ovariectomized rats: biomechanical and molecular analysis

BKN Inoue, LV Paludetto, NG Monteiro… - International Journal of …, 2023 - mdpi.com
Postmenopausal osteoporosis and poor dietary habits can lead to overweightness and
obesity. Bisphosphonates are the first-line treatment for osteoporosis. However, some …

Is the bacterial cellulose membrane feasible for osteopromotive property?

AP Farnezi Bassi, VF Bizelli, LFM Brasil, JC Pereira… - Membranes, 2020 - mdpi.com
Guided bone regeneration was studied to establish protocols and develop new biomaterials
that revealed satisfactory results. The present study aimed to comparatively evaluate the …

Comparison between plasma electrolytic oxidation coating and sandblasted acid-etched surface treatment: histometric, tomographic, and expression levels of …

GAC Momesso, AM de Souza Santos… - Materials, 2020 - mdpi.com
Plasma electrolytic oxidation (PEO) has been a promising surface coating with better
mechanical and antimicrobial parameters comparing to conventional treatment surfaces …

Losartan reverses impaired osseointegration in spontaneously hypertensive rats

G Mulinari-Santos, FR de Souza Batista… - Clinical oral implants …, 2018 - Wiley Online Library
Objective Hypertension is not only associated with cardiovascular diseases but also with
alterations in bone quality. Hypertension therefore might be a risk factor for osseointegration …

Bone repair with raloxifene and bioglass nanoceramic composite in animal experiment

PN Lisboa-Filho, PHS Gomes-Ferreira… - Connective tissue …, 2018 - Taylor & Francis
ABSTRACT OBJECTIVE: This study proposes to evaluate, by means of microtomographic
analysis, the topical potential of raloxifene combined with BioGran® through the …