Antibiotic therapy is the most powerful strategy for treating bacterial infections in clinic.
However, antibiotic resistance has become one of the biggest threats to public health …

Nature embeds some of its molecular machinery, including ion pumps, within lipid bilayer
membranes. This has inspired chemists to attempt to develop synthetic analogues to exploit …

Cationic agents, such as ionic liquids (ILs)-based species, have broad-spectrum
antibacterial activities. However, the antibacterial mechanisms lack systematic and …

The increasing occurrence of antibiotic-resistant bacteria and the dwindling antibiotic
research and development pipeline have created a pressing global health crisis. Here, we …

Bacterial infections seriously threaten human health and also bring huge financial burden. It
is critical to construct multifunctional platforms for effectively inactivating bacteria right after …

Herein, a metal-organic framework (MOF) was modified using polydopamine (PDA) to
develop the MOF-PDA as a photoresponsive bacteria-killing agent under 660 nm light …

The dearth of antibiotic candidates against Gram-negative bacteria and the rise of antibiotic
resistance create a global health concern. The challenge lies in the unique Gram-negative …

Over the last two decades ratchet mechanisms have transformed the understanding and
design of stochastic molecular systems—biological, chemical and physical—in a move away …

Various health agencies, such as the European Medical Agency (EMA), Centers for Disease
Control and Prevention (CDC), and World Health Organization (WHO), timely cited the …

Despite the undisputed development of medicine, antibiotics still serve as first-choice drugs
for patients with infectious disorders. The widespread use of antibiotics results from a wide …